Acquired DNA damage repairs deficiency-driven immune evolution and involved immune factors of local versus distant metastases in non-small cell lung cancer

Acquired DNA damage repairs deficiency-driven immune evolution and involved immune factors of local versus distant metastases in non-small cell lung cancer

ABSTRACTThe evolution of immune profile from primary tumors to distant and local metastases in non-small cell lung cancer (NSCLC), as well as the impact of the immune background of primary tumors on metastatic potential, remains unclear. To address this, we performed whole-exome sequencing and immun...

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Bibliographic Details
Main Authors: Wen-Fang Tang, Xiao-Jun Fan, Hua Bao, Rui Fu, Yi Liang, Min Wu, Chao Zhang, Jian Su, Yi-Long Wu, Wen-Zhao Zhong
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Cancer evolution
metastasis
non-small cell lung cancer
tumor immune microenvironment
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2215112

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