Microtubules provide force to promote membrane uncoating in vacuolar escape for a cyto-invasive bacterial pathogen

Abstract Intracellular bacterial pathogens gain entry to mammalian cells inside a vacuole derived from the host membrane. Some of them escape the bacteria-containing vacuole (BCV) and colonize the cytosol. Bacteria replicating within BCVs coopt the microtubule network to position it within infected...

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Bibliographic Details
Main Authors: Yuen-Yan Chang, Camila Valenzuela, Arthur Lensen, Noelia Lopez-Montero, Saima Sidik, John Salogiannis, Jost Enninga, John Rohde
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45182-6

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