Microtubules provide force to promote membrane uncoating in vacuolar escape for a cyto-invasive bacterial pathogen
Abstract Intracellular bacterial pathogens gain entry to mammalian cells inside a vacuole derived from the host membrane. Some of them escape the bacteria-containing vacuole (BCV) and colonize the cytosol. Bacteria replicating within BCVs coopt the microtubule network to position it within infected...
Main Authors: | Yuen-Yan Chang, Camila Valenzuela, Arthur Lensen, Noelia Lopez-Montero, Saima Sidik, John Salogiannis, Jost Enninga, John Rohde |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-45182-6 |
Similar Items
-
Shigella generates distinct IAM subpopulations during epithelial cell invasion to promote efficient intracellular niche formation
by: Lisa Sanchez, et al.
Published: (2024-03-01) -
Post-translational targeting of Rab35 by the effector IcsB of Shigella determines intracellular bacterial niche formation
by: Nora Mellouk, et al.
Published: (2024-04-01) -
Actin and Microtubules Differently Contribute to Vacuolar Targeting Specificity during the Export from the ER
by: Monica De Caroli, et al.
Published: (2021-04-01) -
Vacuolar Na+/H+ NHX-Type Antiporters Are Required for Cellular K+ Homeostasis, Microtubule Organization and Directional Root Growth
by: Tyler McCubbin, et al.
Published: (2014-08-01) -
Cyto-Neurology in Ischemia
by: Cláudio Roque, et al.
Published: (2022-07-01)