Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014
Background & Objective: Neonatal sepsis is one of the leading causes of mortality in neonatology wards. The aim of this study was to assess sepsis pathogens and antibacterial resistance patterns in a teaching hospital during seven years in Tehran, Iran. Methods: In this retrospective study, all...
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| Format: | Article |
| Language: | English |
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Iranian Society of Pathology
2017-12-01
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| Series: | Iranian Journal of Pathology |
| Subjects: | |
| Online Access: | https://ijp.iranpath.org/article_27992_b0c10a9aa28da03400847aba022ed31b.pdf |
| _version_ | 1819096940903661568 |
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| author | Fatemeh Haj Ebrahim Tehrani Mohammad Moradi Narjes Ghorbani |
| author_facet | Fatemeh Haj Ebrahim Tehrani Mohammad Moradi Narjes Ghorbani |
| author_sort | Fatemeh Haj Ebrahim Tehrani |
| collection | DOAJ |
| description | Background & Objective: Neonatal sepsis is one of the leading causes of mortality in neonatology wards. The aim of this study was to assess sepsis pathogens and antibacterial resistance patterns in a teaching hospital during seven years in Tehran, Iran. Methods: In this retrospective study, all neonates suspected to sepsis and fulfilling the sepsis criteria admitted to NICU ward of Mustafa Khomeini Hospital, Tehran, Iran during 2007 to 2014 were included. Demographic information, blood test results, blood culture results of neonates and antibiogram findings were extracted from their documents. Data was analyzed using SPSS 15. Results:Ninety neonates with positive culture test were included. Fifty-three were male (58.9%). Thirty neonates were delivered vaginally (33.3%) and 60 caesarean section (66.7%). Most bacterial growths in culture were Staphylococcus aureus and E. coli. The rates of resistance for antibiotics like ceftriaxone, cefotaxim and gentamycin were 5%, 30% and 15%, correspondingly. There were 15 cases (16.7%) with resistance to imipenem. Conclusion: Antibacterial resistance patterns vary in different parts of the world and even within a country, therefore assessing resistance patterns in a region is of great importance for proper management and treatment. Our findings might help physicians for proper selection of antibiotics for treatment of neonatal sepsis. |
| first_indexed | 2024-12-22T00:07:11Z |
| format | Article |
| id | doaj.art-b50c8cfba0504474b42438b0da54e174 |
| institution | Directory Open Access Journal |
| issn | 1735-5303 2345-3656 |
| language | English |
| last_indexed | 2024-12-22T00:07:11Z |
| publishDate | 2017-12-01 |
| publisher | Iranian Society of Pathology |
| record_format | Article |
| series | Iranian Journal of Pathology |
| spelling | doaj.art-b50c8cfba0504474b42438b0da54e1742022-12-21T18:45:32ZengIranian Society of PathologyIranian Journal of Pathology1735-53032345-36562017-12-0112435636110.30699/ijp.2017.2799227992Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014Fatemeh Haj Ebrahim Tehrani0Mohammad Moradi1Narjes Ghorbani2Dept. of Neonatology, Shahed Medical Faculty, Shahed University, Tehran, IranStudents Research Committee of Shahed Medical Faculty, Shahed University, Tehran, IranShahed Medical Faculty, Shahed University, Tehran, IranBackground & Objective: Neonatal sepsis is one of the leading causes of mortality in neonatology wards. The aim of this study was to assess sepsis pathogens and antibacterial resistance patterns in a teaching hospital during seven years in Tehran, Iran. Methods: In this retrospective study, all neonates suspected to sepsis and fulfilling the sepsis criteria admitted to NICU ward of Mustafa Khomeini Hospital, Tehran, Iran during 2007 to 2014 were included. Demographic information, blood test results, blood culture results of neonates and antibiogram findings were extracted from their documents. Data was analyzed using SPSS 15. Results:Ninety neonates with positive culture test were included. Fifty-three were male (58.9%). Thirty neonates were delivered vaginally (33.3%) and 60 caesarean section (66.7%). Most bacterial growths in culture were Staphylococcus aureus and E. coli. The rates of resistance for antibiotics like ceftriaxone, cefotaxim and gentamycin were 5%, 30% and 15%, correspondingly. There were 15 cases (16.7%) with resistance to imipenem. Conclusion: Antibacterial resistance patterns vary in different parts of the world and even within a country, therefore assessing resistance patterns in a region is of great importance for proper management and treatment. Our findings might help physicians for proper selection of antibiotics for treatment of neonatal sepsis.https://ijp.iranpath.org/article_27992_b0c10a9aa28da03400847aba022ed31b.pdfneonatal sepsisantibioticsantibiogramresistance |
| spellingShingle | Fatemeh Haj Ebrahim Tehrani Mohammad Moradi Narjes Ghorbani Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014 Iranian Journal of Pathology neonatal sepsis antibiotics antibiogram resistance |
| title | Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014 |
| title_full | Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014 |
| title_fullStr | Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014 |
| title_full_unstemmed | Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014 |
| title_short | Bacterial Etiology and Antibiotic Resistance Patterns in Neonatal Sepsis in Tehran during 2006-2014 |
| title_sort | bacterial etiology and antibiotic resistance patterns in neonatal sepsis in tehran during 2006 2014 |
| topic | neonatal sepsis antibiotics antibiogram resistance |
| url | https://ijp.iranpath.org/article_27992_b0c10a9aa28da03400847aba022ed31b.pdf |
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