Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction

An elevated heart rate at admission or discharge is known to be associated with poor cardiovascular outcomes in patients with acute myocardial infarction (AMI). The association between post-discharge average office-visit heart rate and cardiovascular outcomes in patients with AMI has rarely been stu...

Full description

Bibliographic Details
Main Authors: Jaeho Byeon, Eun Ho Choo, Ik Jun Choi, Kwan Yong Lee, Byung-Hee Hwang, Chan Joon Kim, Doo Soo Jeon, Youngkeun Ahn, Myung Ho Jeong, Kiyuk Chang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/11/3734
_version_ 1797597252935483392
author Jaeho Byeon
Eun Ho Choo
Ik Jun Choi
Kwan Yong Lee
Byung-Hee Hwang
Chan Joon Kim
Doo Soo Jeon
Youngkeun Ahn
Myung Ho Jeong
Kiyuk Chang
author_facet Jaeho Byeon
Eun Ho Choo
Ik Jun Choi
Kwan Yong Lee
Byung-Hee Hwang
Chan Joon Kim
Doo Soo Jeon
Youngkeun Ahn
Myung Ho Jeong
Kiyuk Chang
author_sort Jaeho Byeon
collection DOAJ
description An elevated heart rate at admission or discharge is known to be associated with poor cardiovascular outcomes in patients with acute myocardial infarction (AMI). The association between post-discharge average office-visit heart rate and cardiovascular outcomes in patients with AMI has rarely been studied. We analyzed data for 7840 patients from the COREA-AMI registry who had their heart rates measured at least three times after hospital discharge. The office-visit heart rates were averaged and categorized into four groups by quartiles (<68, 68–74, 74–80, and >80 beats per minute). The primary end point was a composite of cardiovascular death, myocardial infarction, and ischemic stroke. During a median of 5.7 years of follow-up, major adverse cardiovascular events (MACE) affected 1357 (17.3%) patients. An average heart rate higher than 80 bpm was associated with an increased incidence of MACE compared to the reference average heart rate of 68–74 bpm. When dichotomized into <74 or ≥74 bpm, a lower average heart rate was not associated with MACE in patients with LV systolic dysfunction, in contrast to those without LV systolic dysfunction. An elevated average heart rate at office visits after AMI was associated with an increased risk of cardiovascular outcomes. Heart rate monitoring at office visits after discharge provides an important predictor related to cardiovascular events.
first_indexed 2024-03-11T03:03:59Z
format Article
id doaj.art-b513fa0e4b614ebcb9fee352119fa0cf
institution Directory Open Access Journal
issn 2077-0383
language English
last_indexed 2024-03-11T03:03:59Z
publishDate 2023-05-01
publisher MDPI AG
record_format Article
series Journal of Clinical Medicine
spelling doaj.art-b513fa0e4b614ebcb9fee352119fa0cf2023-11-18T08:05:42ZengMDPI AGJournal of Clinical Medicine2077-03832023-05-011211373410.3390/jcm12113734Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial InfarctionJaeho Byeon0Eun Ho Choo1Ik Jun Choi2Kwan Yong Lee3Byung-Hee Hwang4Chan Joon Kim5Doo Soo Jeon6Youngkeun Ahn7Myung Ho Jeong8Kiyuk Chang9Division of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University School of Medicine, Gwangju 61469, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University School of Medicine, Gwangju 61469, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaAn elevated heart rate at admission or discharge is known to be associated with poor cardiovascular outcomes in patients with acute myocardial infarction (AMI). The association between post-discharge average office-visit heart rate and cardiovascular outcomes in patients with AMI has rarely been studied. We analyzed data for 7840 patients from the COREA-AMI registry who had their heart rates measured at least three times after hospital discharge. The office-visit heart rates were averaged and categorized into four groups by quartiles (<68, 68–74, 74–80, and >80 beats per minute). The primary end point was a composite of cardiovascular death, myocardial infarction, and ischemic stroke. During a median of 5.7 years of follow-up, major adverse cardiovascular events (MACE) affected 1357 (17.3%) patients. An average heart rate higher than 80 bpm was associated with an increased incidence of MACE compared to the reference average heart rate of 68–74 bpm. When dichotomized into <74 or ≥74 bpm, a lower average heart rate was not associated with MACE in patients with LV systolic dysfunction, in contrast to those without LV systolic dysfunction. An elevated average heart rate at office visits after AMI was associated with an increased risk of cardiovascular outcomes. Heart rate monitoring at office visits after discharge provides an important predictor related to cardiovascular events.https://www.mdpi.com/2077-0383/12/11/3734acute myocardial infarctionheart ratecardiovascular outcomes
spellingShingle Jaeho Byeon
Eun Ho Choo
Ik Jun Choi
Kwan Yong Lee
Byung-Hee Hwang
Chan Joon Kim
Doo Soo Jeon
Youngkeun Ahn
Myung Ho Jeong
Kiyuk Chang
Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction
Journal of Clinical Medicine
acute myocardial infarction
heart rate
cardiovascular outcomes
title Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction
title_full Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction
title_fullStr Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction
title_full_unstemmed Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction
title_short Office-Visit Heart Rate and Long-Term Cardiovascular Events in Patients with Acute Myocardial Infarction
title_sort office visit heart rate and long term cardiovascular events in patients with acute myocardial infarction
topic acute myocardial infarction
heart rate
cardiovascular outcomes
url https://www.mdpi.com/2077-0383/12/11/3734
work_keys_str_mv AT jaehobyeon officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT eunhochoo officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT ikjunchoi officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT kwanyonglee officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT byungheehwang officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT chanjoonkim officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT doosoojeon officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT youngkeunahn officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT myunghojeong officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction
AT kiyukchang officevisitheartrateandlongtermcardiovasculareventsinpatientswithacutemyocardialinfarction