Meperidine: opioid not indicated for analgesia

BACKGROUND AND OBJECTIVES: Pain evaluation and the choice of the analgesic best providing its control are extremely important for patients’ quality of life. This study aimed at describing the characteristics which make meperidine unfeasible for pain management, at calling the attention to the incide...

Full description

Bibliographic Details
Main Authors: Andresa Graciutti Botan, Simone Aparecida Biazzi de Lapena
Format: Article
Language:English
Published: Sociedade Brasileira para o Estudo da Dor
Series:Revista Dor
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100067&lng=en&tlng=en
_version_ 1818441952678379520
author Andresa Graciutti Botan
Simone Aparecida Biazzi de Lapena
author_facet Andresa Graciutti Botan
Simone Aparecida Biazzi de Lapena
author_sort Andresa Graciutti Botan
collection DOAJ
description BACKGROUND AND OBJECTIVES: Pain evaluation and the choice of the analgesic best providing its control are extremely important for patients’ quality of life. This study aimed at describing the characteristics which make meperidine unfeasible for pain management, at calling the attention to the incidence of its prescriptions and to the need of a multidisciplinary educative action aiming at decreasing its use, in addition to presenting two opioids as options for analgesia. CONTENTS: National or international scientific and governmental publications between the years 1997 and 2013 used in this study report that meperidine is not indicated for pain management, primarily due to its short action time, presence of neurotoxic metabolite (normeperidine) and possibility of rapidly developing tolerance. CONCLUSION: According to analyzed data, meperidine was the most widely used opioid for analgesic or was among the most prescribed analgesics. This fact shows the real need for an educative multidisciplinary action to promote awareness of meperidine risks and to decrease its prescription. According to searched literature, morphine and methadone have longer action time and higher analgesic potency, with metabolites which are less toxic and noxious for patients as compared to meperidine.
first_indexed 2024-12-14T18:36:26Z
format Article
id doaj.art-b51935b7785144dcb38a951e1a613194
institution Directory Open Access Journal
issn 1806-0013
2317-6393
language English
last_indexed 2024-12-14T18:36:26Z
publisher Sociedade Brasileira para o Estudo da Dor
record_format Article
series Revista Dor
spelling doaj.art-b51935b7785144dcb38a951e1a6131942022-12-21T22:51:37ZengSociedade Brasileira para o Estudo da DorRevista Dor1806-00132317-6393161677010.5935/1806-0013.20150013S1806-00132015000100067Meperidine: opioid not indicated for analgesiaAndresa Graciutti BotanSimone Aparecida Biazzi de LapenaBACKGROUND AND OBJECTIVES: Pain evaluation and the choice of the analgesic best providing its control are extremely important for patients’ quality of life. This study aimed at describing the characteristics which make meperidine unfeasible for pain management, at calling the attention to the incidence of its prescriptions and to the need of a multidisciplinary educative action aiming at decreasing its use, in addition to presenting two opioids as options for analgesia. CONTENTS: National or international scientific and governmental publications between the years 1997 and 2013 used in this study report that meperidine is not indicated for pain management, primarily due to its short action time, presence of neurotoxic metabolite (normeperidine) and possibility of rapidly developing tolerance. CONCLUSION: According to analyzed data, meperidine was the most widely used opioid for analgesic or was among the most prescribed analgesics. This fact shows the real need for an educative multidisciplinary action to promote awareness of meperidine risks and to decrease its prescription. According to searched literature, morphine and methadone have longer action time and higher analgesic potency, with metabolites which are less toxic and noxious for patients as compared to meperidine.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100067&lng=en&tlng=enanalgesiadormeperidinametadonamorfina
spellingShingle Andresa Graciutti Botan
Simone Aparecida Biazzi de Lapena
Meperidine: opioid not indicated for analgesia
Revista Dor
analgesia
dor
meperidina
metadona
morfina
title Meperidine: opioid not indicated for analgesia
title_full Meperidine: opioid not indicated for analgesia
title_fullStr Meperidine: opioid not indicated for analgesia
title_full_unstemmed Meperidine: opioid not indicated for analgesia
title_short Meperidine: opioid not indicated for analgesia
title_sort meperidine opioid not indicated for analgesia
topic analgesia
dor
meperidina
metadona
morfina
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100067&lng=en&tlng=en
work_keys_str_mv AT andresagraciuttibotan meperidineopioidnotindicatedforanalgesia
AT simoneaparecidabiazzidelapena meperidineopioidnotindicatedforanalgesia