Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
T cell expansion and differentiation are critically dependent on the transcription factor c-Myc (Myc). Herein we use quantitative mass-spectrometry to reveal how Myc controls antigen receptor driven cell growth and proteome restructuring in murine T cells. Analysis of copy numbers per cell of &g...
Main Authors: | , , , |
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格式: | Article |
語言: | English |
出版: |
eLife Sciences Publications Ltd
2020-02-01
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叢編: | eLife |
主題: | |
在線閱讀: | https://elifesciences.org/articles/53725 |