Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency

Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency

Abstract Background Spinal cord injury (SCI), which causes loss of sensory and motor function in the body below the level of injury, is a devastating disease of the central nervous system. SCI leads to severe secondary immunosuppression, called SCI-induced immunodeficiency syndrome (SCI-IDS), which...

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Hlavní autoři: Hong Zeng, Li Cheng, De-zhi Lu, Shuai Fan, Ke-xin Wang, Li-li Xu, Bin Cai, Mou-wang Zhou, Jin-wu Wang
Médium: Článek
Jazyk:English
Vydáno: BMC 2023-09-01
Edice:Journal of Neuroinflammation
Témata:
SCI-induced immunodeficiency syndrome
Transcriptome
Neuroendocrine immunomodulatory axis
Neuroinflammation
Hypothalamo-pituitary-adrenal axis
On-line přístup:https://doi.org/10.1186/s12974-023-02906-7

Internet

https://doi.org/10.1186/s12974-023-02906-7

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