The AP-1 Transcription Factor Is a Key Determinant of Human Cytomegalovirus Latency and Reactivation

The AP-1 Transcription Factor Is a Key Determinant of Human Cytomegalovirus Latency and Reactivation

Human cytomegalovirus (HCMV) is a ubiquitous pathogen that latently infects hematopoietic progenitor cells (HPCs). Individuals with a competent immune system are, for the most part, asymptomatic for the disease. However when a latently infected individual becomes immunosuppressed, HCMV can reactivat...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Benjamin A. Krishna, Amanda B. Wass, Christine M. O’Connor
Natura:	Articolo
Lingua:	English
Pubblicazione:	MDPI AG 2020-07-01
Serie:	Proceedings
Soggetti:	HCMV cytomegalovirus latency reactivation AP-1 US28
Accesso online:	https://www.mdpi.com/2504-3900/50/1/127

Documenti analoghi

The Requirement for US28 During Cytomegalovirus Latency Is Independent of US27 and US29 Gene Expression
di: Benjamin A. Krishna, et al.
Pubblicazione: (2020-04-01)

Modulation of host cell signaling during cytomegalovirus latency and reactivation
di: Nicholas A. Smith, et al.
Pubblicazione: (2021-10-01)

Human Cytomegalovirus Latency and Reactivation in Allogeneic Hematopoietic Stem Cell Transplant Recipients
di: Lauren Stern, et al.
Pubblicazione: (2019-05-01)

Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34<sup>+</sup> Hematopoietic Progenitor Cells and Humanized NSG Mice
di: Lindsey B. Crawford, et al.
Pubblicazione: (2019-08-01)

Interferon-Responsive Genes Are Targeted during the Establishment of Human Cytomegalovirus Latency
di: Elizabeth G. Elder, et al.
Pubblicazione: (2019-12-01)

Different expression pattern of human cytomegalovirus-encoded microRNAs in circulation from virus latency to reactivation
di: Wanqing Zhou, et al.
Pubblicazione: (2020-12-01)

Regulation of the MIE Locus During HCMV Latency and Reactivation
di: Abigail L. Dooley, et al.
Pubblicazione: (2020-10-01)

Tumor Necrosis Factor Alpha Induces Reactivation of Human Cytomegalovirus Independently of Myeloid Cell Differentiation following Posttranscriptional Establishment of Latency
di: Eleonora Forte, et al.
Pubblicazione: (2018-11-01)

Cytomegalovirus Latency and Reactivation: An Intricate Interplay With the Host Immune Response
di: Eleonora Forte, et al.
Pubblicazione: (2020-03-01)

Expanding the Known Functional Repertoire of the Human Cytomegalovirus pp71 Protein
di: Robert F. Kalejta, et al.
Pubblicazione: (2020-03-01)

Molecular Determinants and the Regulation of Human Cytomegalovirus Latency and Reactivation
di: Donna Collins-McMillen, et al.
Pubblicazione: (2018-08-01)

Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells
di: Benjamin A. Krishna, et al.
Pubblicazione: (2022-06-01)

Cytomegalovirus Infection and Inflammation in Developing Brain
di: Fran Krstanović, et al.
Pubblicazione: (2021-06-01)

Regulation of Latency and Reactivation by Human Cytomegalovirus miRNAs
di: Nicole L. Diggins, et al.
Pubblicazione: (2021-02-01)

Identification of UL69 Gene and Protein in Cytomegalovirus-Transformed Human Mammary Epithelial Cells
di: Sandy Haidar Ahmad, et al.
Pubblicazione: (2021-04-01)

MicroRNA Regulation of Human Herpesvirus Latency
di: Siyu Chen, et al.
Pubblicazione: (2022-06-01)

Regulation of Human Cytomegalovirus Transcription in Latency: Beyond the Major Immediate-Early Promoter
di: John Sinclair, et al.
Pubblicazione: (2013-06-01)

Receptor chimeras demonstrate that the C-terminal domain of the human cytomegalovirus US27 gene product is necessary and sufficient for intracellular receptor localization
di: Stapleton Lance K, et al.
Pubblicazione: (2012-02-01)

The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression
di: Emma Poole, et al.
Pubblicazione: (2023-09-01)

The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts
di: Masatoshi Nukui, et al.
Pubblicazione: (2018-11-01)

The Role of the Human Cytomegalovirus <i>UL133-UL138</i> Gene Locus in Latency and Reactivation
di: Luwanika Mlera, et al.
Pubblicazione: (2020-07-01)

The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients
di: Renata Fragelli Fonseca, et al.
Pubblicazione: (2012-11-01)

Human Cytomegalovirus Induces Vitamin-D Resistance In Vitro by Dysregulating the Transcriptional Repressor Snail
di: Carmen Stecher, et al.
Pubblicazione: (2022-09-01)

Productive Infection of Human Breast Cancer Cell Lines with Human Cytomegalovirus (HCMV)
di: Kaitlin M. Branch, et al.
Pubblicazione: (2021-05-01)

The oncogenic potential of human cytomegalovirus and breast cancer.
di: Georges eHerbein, et al.
Pubblicazione: (2014-08-01)

Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation
di: Sarah E. Jackson, et al.
Pubblicazione: (2021-04-01)

The intimate relationship between Human cytomegalovirus and the dendritic cell lineage
di: John eSinclair, et al.
Pubblicazione: (2014-08-01)

The Viral G-Protein-Coupled Receptor Homologs M33 and US28 Promote Cardiac Dysfunction during Murine Cytomegalovirus Infection
di: Cassandra M. Bonavita, et al.
Pubblicazione: (2023-03-01)

Serological epidemiology analysis of Cytomegalovirus infection in pregnant women in Diwaniyah, Iraq
di: Mohsen Abdul Khadhur Al-Zubaidi, et al.
Pubblicazione: (2025-02-01)

Human cytomegalovirus infection among febrile hematological cancer patients at the Uganda Cancer Institute
di: Ocung Guido, et al.
Pubblicazione: (2024-11-01)

MicroRNAs expressed by human cytomegalovirus
di: Lichen Zhang, et al.
Pubblicazione: (2020-03-01)

Circular RNAs Represent a Novel Class of Human Cytomegalovirus Transcripts
di: Shaomin Yang, et al.
Pubblicazione: (2022-06-01)

Pre-Symptomatic Human Cytomegalovirus Disease Diagnosis in Renal Transplant Recipients by the Virus DNA PCR
di: S Amini-Bavil-Olyaee, et al.
Pubblicazione: (2005-08-01)

Pre-Symptomatic Human Cytomegalovirus Disease Diagnosis in Renal Transplant Recipients by the Virus DNA PCR
di: S Amini-Bavil-Olyaee, et al.
Pubblicazione: (2005-09-01)

EZH2-Myc Hallmark in Oncovirus/Cytomegalovirus Infections and Cytomegalovirus’ Resemblance to Oncoviruses
di: Ranim El Baba, et al.
Pubblicazione: (2024-03-01)

NK Cell Memory to Cytomegalovirus: Implications for Vaccine Development
di: Calum Forrest, et al.
Pubblicazione: (2020-07-01)

Interplay Between Calcium and AMPK Signaling in Human Cytomegalovirus Infection
di: Diana M. Dunn, et al.
Pubblicazione: (2020-07-01)

Activation of Langerhans-type dendritic cells alters human cytomegalovirus infection and reactivation in a stimulus-dependent manner.
di: Roxanne Coronel, et al.
Pubblicazione: (2016-09-01)

Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes
di: Miho Shibamura, et al.
Pubblicazione: (2020-08-01)

Human Cytomegalovirus Interleukin 10 Homologs: Facing the Immune System
di: Emma Poole, et al.
Pubblicazione: (2020-06-01)