Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study

BackgroundHIV disproportionately affects young Thai men who have sex with men (YMSM). Recent studies report a high incidence and prevalence of HIV among Thai YMSM. The Thai national guidelines have recommended pre-exposure prophylaxis (PrEP) since 2014 for key populations; fr...

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Main Authors: Wipaporn Natalie Songtaweesin, Sara LeGrand, Shashika Bandara, Caitlin Piccone, Prissana Wongharn, Juthamanee Moonwong, Thidarat Jupimai, Chutima Saisaengjan, Tuangtip Theerawit, Kathryn Muessig, Lisa Hightow-Weidman, Thanyawee Puthanakit, Nittaya Phanuphak, Arunrat Tangmunkongvorakul
Format: Article
Language:English
Published: JMIR Publications 2021-11-01
Series:Journal of Medical Internet Research
Online Access:https://www.jmir.org/2021/11/e23852
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author Wipaporn Natalie Songtaweesin
Sara LeGrand
Shashika Bandara
Caitlin Piccone
Prissana Wongharn
Juthamanee Moonwong
Thidarat Jupimai
Chutima Saisaengjan
Tuangtip Theerawit
Kathryn Muessig
Lisa Hightow-Weidman
Thanyawee Puthanakit
Nittaya Phanuphak
Arunrat Tangmunkongvorakul
author_facet Wipaporn Natalie Songtaweesin
Sara LeGrand
Shashika Bandara
Caitlin Piccone
Prissana Wongharn
Juthamanee Moonwong
Thidarat Jupimai
Chutima Saisaengjan
Tuangtip Theerawit
Kathryn Muessig
Lisa Hightow-Weidman
Thanyawee Puthanakit
Nittaya Phanuphak
Arunrat Tangmunkongvorakul
author_sort Wipaporn Natalie Songtaweesin
collection DOAJ
description BackgroundHIV disproportionately affects young Thai men who have sex with men (YMSM). Recent studies report a high incidence and prevalence of HIV among Thai YMSM. The Thai national guidelines have recommended pre-exposure prophylaxis (PrEP) since 2014 for key populations; free PrEP has been piloted since 2019. Smartphone-based mobile health (mHealth) interventions provide an optimal platform for innovative PrEP adherence interventions for Thai YMSM. ObjectiveThis study aims to adapt the P3 (Prepared, Protected, emPowered) app, developed with YMSM and transwomen in the United States to improve PrEP adherence and persistence for YMSM in Thailand. The app aims to provide daily adherence support and addresses gaps in staff available for large-scale PrEP rollout needed to see population-level effects of HIV prevention. MethodsWe conducted focus group discussions (FGDs) with YMSM and key informant interviews (KIIs) with PrEP care providers in Bangkok, Thailand, to investigate PrEP adherence facilitators and barriers, preferences for functions and features in mHealth apps among YMSM, and how to best adapt the P3 app to the Thai context. We conducted four FGDs with 4-8 participants per group and 15 KIIs. ResultsFor FGDs, 23 YMSM participated with a mean age of 20 years (range 18-21), 96% (22/23) enrolled in full-time education, and all owned smartphones. The mean age of KII participants was 40 (range 26-60) years; most were state health service providers, with the majority being counselors (6/15, 40%) and physicians (6/15, 40%). Overall, the facilitators and barriers for PrEP adherence identified were similar to those of MSM and YMSM globally including the United States. Key themes included general recommendations for improving mHealth apps in Thailand, such as presenting reliable information in an appealing format, minimizing privacy risks, and addressing connectivity challenges. Additional themes focused on P3 Thailand adaptations and were related to cultural and stylistic preferences, engagement strategies, and recommendations for new functions. To develop the adapted app, P3 Thailand, these findings were balanced with resource limitations resulting in the prioritization of minor modifications: changes in app esthetics (color scheme, iconography, and imagery) and changes in the presentation of information in two of the app’s features. FGDs identified similar PrEP adherence facilitators and barriers to those already addressed within the app. ConclusionsThe core elements of the P3 app address major PrEP facilitators and barriers for Thai YMSM; however, changes to the app features, including stylistic presentation, were needed to appropriately customize the app to the Thai context. Given the similarities of facilitators and barriers for PrEP adherence globally, adapting existing PrEP mHealth solutions based on input from end users and key informants provides a promising approach. However, partnerships with local app designers and developers can improve the adaptation process and final product. Trial RegistrationClinicalTrials.gov NCT04413708; http://clinicaltrials.gov/ct2/show/NCT04413708
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spelling doaj.art-b51b5c6954dd4105a96975f5da24b5572023-08-28T19:43:47ZengJMIR PublicationsJournal of Medical Internet Research1438-88712021-11-012311e2385210.2196/23852Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative StudyWipaporn Natalie Songtaweesinhttps://orcid.org/0000-0003-3440-732XSara LeGrandhttps://orcid.org/0000-0002-2590-516XShashika Bandarahttps://orcid.org/0000-0002-1698-138XCaitlin Picconehttps://orcid.org/0000-0003-4575-4853Prissana Wongharnhttps://orcid.org/0000-0002-4245-0419Juthamanee Moonwonghttps://orcid.org/0000-0002-9840-2168Thidarat Jupimaihttps://orcid.org/0000-0002-0051-2490Chutima Saisaengjanhttps://orcid.org/0000-0003-4044-0951Tuangtip Theerawithttps://orcid.org/0000-0003-1296-4344Kathryn Muessighttps://orcid.org/0000-0002-8522-3240Lisa Hightow-Weidmanhttps://orcid.org/0000-0002-2421-923XThanyawee Puthanakithttps://orcid.org/0000-0003-1873-1867Nittaya Phanuphakhttps://orcid.org/0000-0002-0036-3165Arunrat Tangmunkongvorakulhttps://orcid.org/0000-0002-9096-6372 BackgroundHIV disproportionately affects young Thai men who have sex with men (YMSM). Recent studies report a high incidence and prevalence of HIV among Thai YMSM. The Thai national guidelines have recommended pre-exposure prophylaxis (PrEP) since 2014 for key populations; free PrEP has been piloted since 2019. Smartphone-based mobile health (mHealth) interventions provide an optimal platform for innovative PrEP adherence interventions for Thai YMSM. ObjectiveThis study aims to adapt the P3 (Prepared, Protected, emPowered) app, developed with YMSM and transwomen in the United States to improve PrEP adherence and persistence for YMSM in Thailand. The app aims to provide daily adherence support and addresses gaps in staff available for large-scale PrEP rollout needed to see population-level effects of HIV prevention. MethodsWe conducted focus group discussions (FGDs) with YMSM and key informant interviews (KIIs) with PrEP care providers in Bangkok, Thailand, to investigate PrEP adherence facilitators and barriers, preferences for functions and features in mHealth apps among YMSM, and how to best adapt the P3 app to the Thai context. We conducted four FGDs with 4-8 participants per group and 15 KIIs. ResultsFor FGDs, 23 YMSM participated with a mean age of 20 years (range 18-21), 96% (22/23) enrolled in full-time education, and all owned smartphones. The mean age of KII participants was 40 (range 26-60) years; most were state health service providers, with the majority being counselors (6/15, 40%) and physicians (6/15, 40%). Overall, the facilitators and barriers for PrEP adherence identified were similar to those of MSM and YMSM globally including the United States. Key themes included general recommendations for improving mHealth apps in Thailand, such as presenting reliable information in an appealing format, minimizing privacy risks, and addressing connectivity challenges. Additional themes focused on P3 Thailand adaptations and were related to cultural and stylistic preferences, engagement strategies, and recommendations for new functions. To develop the adapted app, P3 Thailand, these findings were balanced with resource limitations resulting in the prioritization of minor modifications: changes in app esthetics (color scheme, iconography, and imagery) and changes in the presentation of information in two of the app’s features. FGDs identified similar PrEP adherence facilitators and barriers to those already addressed within the app. ConclusionsThe core elements of the P3 app address major PrEP facilitators and barriers for Thai YMSM; however, changes to the app features, including stylistic presentation, were needed to appropriately customize the app to the Thai context. Given the similarities of facilitators and barriers for PrEP adherence globally, adapting existing PrEP mHealth solutions based on input from end users and key informants provides a promising approach. However, partnerships with local app designers and developers can improve the adaptation process and final product. Trial RegistrationClinicalTrials.gov NCT04413708; http://clinicaltrials.gov/ct2/show/NCT04413708https://www.jmir.org/2021/11/e23852
spellingShingle Wipaporn Natalie Songtaweesin
Sara LeGrand
Shashika Bandara
Caitlin Piccone
Prissana Wongharn
Juthamanee Moonwong
Thidarat Jupimai
Chutima Saisaengjan
Tuangtip Theerawit
Kathryn Muessig
Lisa Hightow-Weidman
Thanyawee Puthanakit
Nittaya Phanuphak
Arunrat Tangmunkongvorakul
Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study
Journal of Medical Internet Research
title Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study
title_full Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study
title_fullStr Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study
title_full_unstemmed Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study
title_short Adaptation of a Theory-Based Social Networking and Gamified App-Based Intervention to Improve Pre-Exposure Prophylaxis Adherence Among Young Men Who Have Sex With Men in Bangkok, Thailand: Qualitative Study
title_sort adaptation of a theory based social networking and gamified app based intervention to improve pre exposure prophylaxis adherence among young men who have sex with men in bangkok thailand qualitative study
url https://www.jmir.org/2021/11/e23852
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