Effects of Focused-Ultrasound-and-Microbubble-Induced Blood-Brain Barrier Disruption on Drug Transport under Liposome-Mediated Delivery in Brain Tumour: A Pilot Numerical Simulation Study
Focused ultrasound (FUS) coupled with microbubbles (MB) has been found to be a promising approach to disrupt the blood-brain barrier (BBB). However, how this disruption affects drug transport remains unclear. In this study, drug transport in combination therapy of liposomes and FUS-MB-induced BBB di...
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| Format: | Article |
| Sprog: | English |
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MDPI AG
2020-01-01
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| Serier: | Pharmaceutics |
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| Online adgang: | https://www.mdpi.com/1999-4923/12/1/69 |