Effects of Focused-Ultrasound-and-Microbubble-Induced Blood-Brain Barrier Disruption on Drug Transport under Liposome-Mediated Delivery in Brain Tumour: A Pilot Numerical Simulation Study

Focused ultrasound (FUS) coupled with microbubbles (MB) has been found to be a promising approach to disrupt the blood-brain barrier (BBB). However, how this disruption affects drug transport remains unclear. In this study, drug transport in combination therapy of liposomes and FUS-MB-induced BBB di...

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Detalles Bibliográficos
Autor Principal: Wenbo Zhan
Formato: Artigo
Idioma:English
Publicado: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
Acceso en liña:https://www.mdpi.com/1999-4923/12/1/69