Renal control of life-threatening malarial anemia

Renal control of life-threatening malarial anemia

Summary: Iron recycling prevents the development of anemia under homeostatic conditions. Whether iron recycling was co-opted as a defense strategy to prevent the development of anemia in response to infection is unclear. We find that in severe Plasmodium falciparum malaria, the onset of life-threate...

Полное описание

Библиографические подробности
Главные авторы:	Qian Wu, Euclides Sacomboio, Lara Valente de Souza, Rui Martins, Jamil Kitoko, Sílvia Cardoso, Temitope W. Ademolue, Tiago Paixão, Jaakko Lehtimäki, Ana Figueiredo, Caren Norden, Pierre-Louis Tharaux, Guenter Weiss, Fudi Wang, Susana Ramos, Miguel P. Soares
Формат:	Статья
Язык:	English
Опубликовано:	Elsevier 2023-02-01
Серии:	Cell Reports
Предметы:	CP: Immunology
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2211124723000682

Схожие документы

The immune landscape of murine skeletal muscle regeneration and aging
по: Neuza S. Sousa, и др.
Опубликовано: (2024-11-01)

RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery
по: Tao Yang, и др.
Опубликовано: (2023-10-01)

SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
по: Laura Griewahn, и др.
Опубликовано: (2023-01-01)

BATF2 is a regulator of interferon-γ signaling in astrocytes during neuroinflammation
по: Rachel A. Tinkey, и др.
Опубликовано: (2025-03-01)

Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity
по: Shayla R. Mosley, и др.
Опубликовано: (2025-02-01)

Pathogenic role for CD101-negative neutrophils in the type I interferon-mediated immunopathogenesis of tuberculosis
по: Mohd Saqib, и др.
Опубликовано: (2025-01-01)

Multi-omics reveals immune response and metabolic profiles during high-altitude mountaineering
по: Jianhua Yin, и др.
Опубликовано: (2025-01-01)

Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance
по: Qiang Tang, и др.
Опубликовано: (2025-01-01)

Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes
по: Katarina Wendy Schmidt, и др.
Опубликовано: (2024-12-01)

Cytokines reprogram airway sensory neurons in asthma
по: Theo Crosson, и др.
Опубликовано: (2024-12-01)

Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity
по: Anna-Marie Pedde, и др.
Опубликовано: (2024-11-01)

A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling
по: Bodie Curren, и др.
Опубликовано: (2024-11-01)

IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
по: Lei Zhao, и др.
Опубликовано: (2024-12-01)

Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
по: Dongmin Chun, и др.
Опубликовано: (2024-12-01)

Microenvironmental β-TrCP negates amino acid transport to trigger CD8+ T cell exhaustion in human non-small cell lung cancer
по: Ge Li, и др.
Опубликовано: (2025-01-01)

Defective removal of invariant chain peptides from MHC class II suppresses tumor antigen presentation and promotes tumor growth
по: Joanna Bandola-Simon, и др.
Опубликовано: (2025-01-01)

Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells
по: Luciana Melo Garcia, и др.
Опубликовано: (2025-01-01)

NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression
по: Wenchao Xu, и др.
Опубликовано: (2025-02-01)

Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation
по: Leigh Ellen Fremuth, и др.
Опубликовано: (2025-01-01)

Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
по: Madison R. Mix, и др.
Опубликовано: (2025-02-01)

Platelets tune fear memory in mice
по: Stefano Garofalo, и др.
Опубликовано: (2025-02-01)

Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice
по: Fabiola Silva Angulo, и др.
Опубликовано: (2025-02-01)

ECM29/proteasome-mediated self-antigen generation by CNS-resident neuroglia promotes regulatory T cell activation
по: Sheng-Wen Chen, и др.
Опубликовано: (2025-01-01)

Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine
по: Juliana Escher Toller-Kawahisa, и др.
Опубликовано: (2025-01-01)

Litomosoides sigmodontis microfilariae-induced eosinophil ETosis is dependent on the canonical inflammasome pathway
по: Alexandra Ehrens, и др.
Опубликовано: (2025-01-01)

Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy
по: Paulo Pereira, и др.
Опубликовано: (2025-03-01)

DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity
по: Yuqing Wu, и др.
Опубликовано: (2025-03-01)

Hexokinase 2-mediated metabolic stress and inflammation burden of liver macrophages via histone lactylation in MASLD
по: Jinyang Li, и др.
Опубликовано: (2025-03-01)

Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling
по: Chae Min Yuk, и др.
Опубликовано: (2025-02-01)

A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy
по: William W. Tang, и др.
Опубликовано: (2025-02-01)

Integrated metabolic-transcriptomic network identifies immunometabolic modulations in human macrophages
по: Hung-Jen Chen, и др.
Опубликовано: (2024-09-01)

The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring
по: Chunxiang Shen, и др.
Опубликовано: (2024-10-01)

Investigation of MSC potency metrics via integration of imaging modalities with lipidomic characterization
по: Priyanka Priyadarshani, и др.
Опубликовано: (2024-08-01)

Disruption of glucose homeostasis by bacterial infection orchestrates host innate immunity through NAD+/NADH balance
по: Jingjing Tang, и др.
Опубликовано: (2024-09-01)

Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
по: David Jetton, и др.
Опубликовано: (2024-08-01)

Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection
по: Mack B. Reynolds, и др.
Опубликовано: (2024-08-01)

terraFlow, a high-parameter analysis tool, reveals T cell exhaustion and dysfunctional cytokine production in classical Hodgkin’s lymphoma
по: Daniel Freeman, и др.
Опубликовано: (2024-08-01)

Lipid-associated macrophages for osimertinib resistance and leptomeningeal metastases in NSCLC
по: Yang-Si Li, и др.
Опубликовано: (2024-08-01)

CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism
по: Xin Zhang, и др.
Опубликовано: (2024-09-01)

Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
по: Sander de Kivit, и др.
Опубликовано: (2024-09-01)