Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring
A novel micro-needle array electrode (MAE) fabricated by thermal drawing and coated with Ti/Au film was proposed for bio-signals monitoring. A simple and effective setup was employed to form glassy-state poly (lactic-co-glycolic acid) (PLGA) into a micro-needle array (MA) by the thermal drawing meth...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
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MDPI AG
2016-06-01
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| মালা: | Sensors |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | http://www.mdpi.com/1424-8220/16/6/908 |
| _version_ | 1828117813923938304 |
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| author | Lei Ren Qing Jiang Keyun Chen Zhipeng Chen Chengfeng Pan Lelun Jiang |
| author_facet | Lei Ren Qing Jiang Keyun Chen Zhipeng Chen Chengfeng Pan Lelun Jiang |
| author_sort | Lei Ren |
| collection | DOAJ |
| description | A novel micro-needle array electrode (MAE) fabricated by thermal drawing and coated with Ti/Au film was proposed for bio-signals monitoring. A simple and effective setup was employed to form glassy-state poly (lactic-co-glycolic acid) (PLGA) into a micro-needle array (MA) by the thermal drawing method. The MA was composed of 6 × 6 micro-needles with an average height of about 500 μm. Electrode-skin interface impedance (EII) was recorded as the insertion force was applied on the MAE. The insertion process of the MAE was also simulated by the finite element method. Results showed that MAE could insert into skin with a relatively low compression force and maintain stable contact impedance between the MAE and skin. Bio-signals, including electromyography (EMG), electrocardiography (ECG), and electroencephalograph (EEG) were also collected. Test results showed that the MAE could record EMG, ECG, and EEG signals with good fidelity in shape and amplitude in comparison with the commercial Ag/AgCl electrodes, which proves that MAE is an alternative electrode for bio-signals monitoring. |
| first_indexed | 2024-04-11T13:20:33Z |
| format | Article |
| id | doaj.art-b51cf4a66aaf4a2598a150ea51e8eba2 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T13:20:33Z |
| publishDate | 2016-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-b51cf4a66aaf4a2598a150ea51e8eba22022-12-22T04:22:12ZengMDPI AGSensors1424-82202016-06-0116690810.3390/s16060908s16060908Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals MonitoringLei Ren0Qing Jiang1Keyun Chen2Zhipeng Chen3Chengfeng Pan4Lelun Jiang5Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-Sen University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-Sen University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-Sen University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-Sen University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-Sen University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-Sen University, Guangzhou 510006, ChinaA novel micro-needle array electrode (MAE) fabricated by thermal drawing and coated with Ti/Au film was proposed for bio-signals monitoring. A simple and effective setup was employed to form glassy-state poly (lactic-co-glycolic acid) (PLGA) into a micro-needle array (MA) by the thermal drawing method. The MA was composed of 6 × 6 micro-needles with an average height of about 500 μm. Electrode-skin interface impedance (EII) was recorded as the insertion force was applied on the MAE. The insertion process of the MAE was also simulated by the finite element method. Results showed that MAE could insert into skin with a relatively low compression force and maintain stable contact impedance between the MAE and skin. Bio-signals, including electromyography (EMG), electrocardiography (ECG), and electroencephalograph (EEG) were also collected. Test results showed that the MAE could record EMG, ECG, and EEG signals with good fidelity in shape and amplitude in comparison with the commercial Ag/AgCl electrodes, which proves that MAE is an alternative electrode for bio-signals monitoring.http://www.mdpi.com/1424-8220/16/6/908micro-needle arrayelectrodeimpedanceEMGECGEEGfinite element method |
| spellingShingle | Lei Ren Qing Jiang Keyun Chen Zhipeng Chen Chengfeng Pan Lelun Jiang Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring Sensors micro-needle array electrode impedance EMG ECG EEG finite element method |
| title | Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring |
| title_full | Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring |
| title_fullStr | Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring |
| title_full_unstemmed | Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring |
| title_short | Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring |
| title_sort | fabrication of a micro needle array electrode by thermal drawing for bio signals monitoring |
| topic | micro-needle array electrode impedance EMG ECG EEG finite element method |
| url | http://www.mdpi.com/1424-8220/16/6/908 |
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