Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance
Mycobacterium tuberculosis (TB) infection of the penis is a rare but serious problem. We report a case of penile TB in a 75-year-old man who presented with fever and dyspnea. No active lung lesions except pleural and pericardial effusion were found on chest X-ray. Monoclonal gammopathy of undetermin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2006-01-01
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| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664609602035 |
| _version_ | 1818318956092456960 |
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| author | Wilfred C.H. Wu Shyh-Chyan Chen Ju-Ton Hsieh Jun Chen Hong-Chiang Chang |
| author_facet | Wilfred C.H. Wu Shyh-Chyan Chen Ju-Ton Hsieh Jun Chen Hong-Chiang Chang |
| author_sort | Wilfred C.H. Wu |
| collection | DOAJ |
| description | Mycobacterium tuberculosis (TB) infection of the penis is a rare but serious problem. We report a case of penile TB in a 75-year-old man who presented with fever and dyspnea. No active lung lesions except pleural and pericardial effusion were found on chest X-ray. Monoclonal gammopathy of undetermined significance was diagnosed after serum and urine electrophoresis studies, and repeated bone marrow studies. Genital examination showed diffuse papulonecrotic skin ulcers involving the whole penile shaft, extending ventrally to the median raphe of the scrotum. Pus smear showed positive acid-fast stain, and culture yielded M. tuberculosis. Culture of pleural and pericardial effusion was also positive for M. tuberculosis. Anti-TB treatment was given with isoniazid, ethambutol, rifampin and pyrazinamide, and the cutaneous lesion was noted to be healed at follow-up 6 months later. Although rare, the possibility of TB as a cause of genital ulcer should be kept in mind. |
| first_indexed | 2024-12-13T10:01:27Z |
| format | Article |
| id | doaj.art-b51d46dcfb8b4bfe89f45278e5557115 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-13T10:01:27Z |
| publishDate | 2006-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-b51d46dcfb8b4bfe89f45278e55571152022-12-21T23:51:38ZengElsevierJournal of the Formosan Medical Association0929-66462006-01-01105975375510.1016/S0929-6646(09)60203-5Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined SignificanceWilfred C.H. WuShyh-Chyan ChenJu-Ton HsiehJun ChenHong-Chiang ChangMycobacterium tuberculosis (TB) infection of the penis is a rare but serious problem. We report a case of penile TB in a 75-year-old man who presented with fever and dyspnea. No active lung lesions except pleural and pericardial effusion were found on chest X-ray. Monoclonal gammopathy of undetermined significance was diagnosed after serum and urine electrophoresis studies, and repeated bone marrow studies. Genital examination showed diffuse papulonecrotic skin ulcers involving the whole penile shaft, extending ventrally to the median raphe of the scrotum. Pus smear showed positive acid-fast stain, and culture yielded M. tuberculosis. Culture of pleural and pericardial effusion was also positive for M. tuberculosis. Anti-TB treatment was given with isoniazid, ethambutol, rifampin and pyrazinamide, and the cutaneous lesion was noted to be healed at follow-up 6 months later. Although rare, the possibility of TB as a cause of genital ulcer should be kept in mind.http://www.sciencedirect.com/science/article/pii/S0929664609602035antibodygenitourinarymultiple myelomamycobacterium |
| spellingShingle | Wilfred C.H. Wu Shyh-Chyan Chen Ju-Ton Hsieh Jun Chen Hong-Chiang Chang Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance Journal of the Formosan Medical Association antibody genitourinary multiple myeloma mycobacterium |
| title | Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance |
| title_full | Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance |
| title_fullStr | Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance |
| title_full_unstemmed | Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance |
| title_short | Penile Tuberculosis Associated with Monoclonal Gammopathy of Undetermined Significance |
| title_sort | penile tuberculosis associated with monoclonal gammopathy of undetermined significance |
| topic | antibody genitourinary multiple myeloma mycobacterium |
| url | http://www.sciencedirect.com/science/article/pii/S0929664609602035 |
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