Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic modifications and alterations in chromatin structure and function contribute to the cumulative changes observed as normal cells undergo malignant transformation. These modifications and enzymes (DNA methyltransferases, histone deacetylases, histone methyltransferases, and demethylases) re...

ver descrição completa

Detalhes bibliográficos
Main Authors: Manisha Sachan, Manpreet Kaur
Formato: Artigo
Idioma:English
Publicado em: Instituto de Tecnologia do Paraná (Tecpar) 2015-08-01
Colecção:Brazilian Archives of Biology and Technology
Assuntos:
HDAC inhibitors
Cancer epigenetics
Histone modification
Acesso em linha:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400526&lng=en&tlng=en

Registos relacionados

Registos relacionados