Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic modifications and alterations in chromatin structure and function contribute to the cumulative changes observed as normal cells undergo malignant transformation. These modifications and enzymes (DNA methyltransferases, histone deacetylases, histone methyltransferases, and demethylases) re...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Manisha Sachan, Manpreet Kaur
Định dạng:	Bài viết
Ngôn ngữ:	English
Được phát hành:	Instituto de Tecnologia do Paraná (Tecpar) 2015-08-01
Loạt:	Brazilian Archives of Biology and Technology
Những chủ đề:	HDAC inhibitors Cancer epigenetics Histone modification
Truy cập trực tuyến:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400526&lng=en&tlng=en

Những quyển sách tương tự

Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics
Bằng: Michelle Esposito, et al.
Được phát hành: (2019-05-01)

The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
Bằng: Guo Li, et al.
Được phát hành: (2020-09-01)

Implication des modifications épigénétiques dans les cancers : développement de nouvelles approches thérapeutiques
Bằng: Willems L., et al.
Được phát hành: (2008-01-01)

Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
Bằng: Xiaomin Wang, et al.
Được phát hành: (2023-06-01)

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors
Bằng: Delcuve Geneviève P, et al.
Được phát hành: (2012-03-01)

The therapeutic potential of class I selective histone deacetylase inhibitors in ovarian cancer
Bằng: Dineo eKhabele
Được phát hành: (2014-05-01)

dCas9-HDAC8-EGFP fusion enables epigenetic editing of breast cancer cells by H3K9 deacetylation
Bằng: Mohammad Mijanur Rahman, et al.
Được phát hành: (2024-12-01)

Interaction of ncRNA and Epigenetic Modifications in Gastric Cancer: Focus on Histone Modification
Bằng: Qingfan Yang, et al.
Được phát hành: (2022-01-01)

Epigenetic regulation by gut microbiota
Bằng: Vivienne Woo, et al.
Được phát hành: (2022-12-01)

Epigenetic modification enzymes: catalytic mechanisms and inhibitors
Bằng: Duo Lu
Được phát hành: (2013-05-01)

Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
Bằng: Dusan Ruzic, et al.
Được phát hành: (2022-01-01)

Epigenetic control of the vicious cycle
Bằng: Madeline B. Searcy, et al.
Được phát hành: (2024-02-01)

The role of HDAC3 in inflammation: mechanisms and therapeutic implications
Bằng: Noah Watson, et al.
Được phát hành: (2024-07-01)

The Emerging Roles and Therapeutic Implications of Epigenetic Modifications in Ovarian Cancer
Bằng: Yu Wang, et al.
Được phát hành: (2022-05-01)

Epigenetics in Inflammatory Breast Cancer: Biological Features and Therapeutic Perspectives
Bằng: Flavia Lima Costa Faldoni, et al.
Được phát hành: (2020-05-01)

Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer
Bằng: Xilan Yu, et al.
Được phát hành: (2018-09-01)

Histones and their modifications in ovarian cancer – drivers of disease and therapeutic targets
Bằng: Deborah Joy Marsh, et al.
Được phát hành: (2014-06-01)

EPIGENETIC EFFECTS OF ENZASTAURIN – A NEW ASPECT IN THE MECHANISM OF ACTION OF AN ANTICANCER DRUG FROM PROTEIN KINASE INHIBITORS
Bằng: V. P. Maksimova, et al.
Được phát hành: (2020-09-01)

From Bench to Bedside: Targeting Epigenetics for Cancer Therapy
Bằng: Jin-xu Fang, et al.
Được phát hành: (2011-12-01)

Mechanisms and technologies in cancer epigenetics
Bằng: Zaki A. Sherif, et al.
Được phát hành: (2025-01-01)

Histone Deacetylases and their Inhibitors in Cancer Epigenetics
Bằng: Kelly N. Hassell
Được phát hành: (2019-11-01)

Cellular Epigenetic Targets and Epidrugs in Breast Cancer Therapy: Mechanisms, Challenges, and Future Perspectives
Bằng: Ibrahim S. Alalhareth, et al.
Được phát hành: (2025-02-01)

Histone deacetylase inhibition leads to regulatory histone mark alterations and impairs meiosis in oocytes
Bằng: Louis Legoff, et al.
Được phát hành: (2021-08-01)

Epigenetic modifications: Key players in cancer heterogeneity and drug resistance
Bằng: Hana Q. Sadida, et al.
Được phát hành: (2024-01-01)

The proteasome and epigenetics: zooming in on histone modifications
Bằng: Bach Svitlana V., et al.
Được phát hành: (2016-08-01)

New Insight in HDACs: Potential Therapeutic Targets for the Treatment of Atherosclerosis
Bằng: Yi Luan, et al.
Được phát hành: (2022-04-01)

Epigenetics modifications and therapeutic prospects in human thyroid cancer
Bằng: Maria Graziella eCatalano, et al.
Được phát hành: (2012-03-01)

Histone deacetylases and their inhibitors: molecular mechanisms and therapeutic implications in diabetes mellitus
Bằng: Xiaojie Wang, et al.
Được phát hành: (2012-08-01)

Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
Bằng: Vera Miranda-Gonçalves, et al.
Được phát hành: (2018-10-01)

Connections between metabolism and epigenetic modifications in cancer
Bằng: Wang Guangchao, et al.
Được phát hành: (2021-12-01)

Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy
Bằng: Wenjing Xiao, et al.
Được phát hành: (2021-09-01)

Drugs Targeting Epigenetic Modifications and Plausible Therapeutic Strategies Against Colorectal Cancer
Bằng: Srinivas Patnaik, et al.
Được phát hành: (2019-06-01)

Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology
Bằng: Maria R. Pozo, et al.
Được phát hành: (2022-01-01)

Corrigendum: Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
Bằng: Vera Miranda-Gonçalves, et al.
Được phát hành: (2019-09-01)

Intersection of Epigenetic and Metabolic Regulation of Histone Modifications in Acute Myeloid Leukemia
Bằng: Abhinav Dhall, et al.
Được phát hành: (2019-05-01)

Deciphering the potential role of post-translational modifications of histones in gastrointestinal cancers: a proteomics-based review with therapeutic challenges and opportunities
Bằng: Reyhaneh Farrokhi Yekta, et al.
Được phát hành: (2024-10-01)

Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression
Bằng: Reem Saleh, et al.
Được phát hành: (2020-07-01)

Epigenetic Modifications of Host Genes Induced by Bacterial Infection
Bằng: Maryam Parhamfar, et al.
Được phát hành: (2021-08-01)

NSD family proteins: Rising stars as therapeutic targets
Bằng: Lin He, et al.
Được phát hành: (2024-04-01)

Pulmonary Pathogen-Induced Epigenetic Modifications
Bằng: Dylan Wrede, et al.
Được phát hành: (2023-07-01)