Synthesis of Two Novel Azilsartan Cocrystals: Preparation, Physicochemical Characterization and Solubility Studies

Azilsartan is a novel angiotension II receptor blocker primarily used to treat high blood pressure. This is not a formulation-friendly molecule largely due to the inherent water-solubility pitfalls. In this paper, two novel cocrystals of azilsartan (AZ) were studied (AZ-BIP, AZ-BPE; BIP = 4,4′-bipyr...

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Hlavní autoři: Lei Gao, Xian-Rui Zhang
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2020-08-01
Edice:Crystals
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On-line přístup:https://www.mdpi.com/2073-4352/10/9/739