Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite
The authors report here the structure-function analysis of highly divergent actin from Leishmania parasite. The study reveals remarkably rapid dynamics of parasite actin as well as the underlying molecular basis, thus providing insight into evolution of the actin cytoskeleton.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31068-y |
| _version_ | 1811242162017271808 |
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| author | Tommi Kotila Hugo Wioland Muniyandi Selvaraj Konstantin Kogan Lina Antenucci Antoine Jégou Juha T. Huiskonen Guillaume Romet-Lemonne Pekka Lappalainen |
| author_facet | Tommi Kotila Hugo Wioland Muniyandi Selvaraj Konstantin Kogan Lina Antenucci Antoine Jégou Juha T. Huiskonen Guillaume Romet-Lemonne Pekka Lappalainen |
| author_sort | Tommi Kotila |
| collection | DOAJ |
| description | The authors report here the structure-function analysis of highly divergent actin from Leishmania parasite. The study reveals remarkably rapid dynamics of parasite actin as well as the underlying molecular basis, thus providing insight into evolution of the actin cytoskeleton. |
| first_indexed | 2024-04-12T13:47:42Z |
| format | Article |
| id | doaj.art-b51e8c37b37c487a80e957a5cb198fc3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T13:47:42Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b51e8c37b37c487a80e957a5cb198fc32022-12-22T03:30:38ZengNature PortfolioNature Communications2041-17232022-06-0113111810.1038/s41467-022-31068-yStructural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasiteTommi Kotila0Hugo Wioland1Muniyandi Selvaraj2Konstantin Kogan3Lina Antenucci4Antoine Jégou5Juha T. Huiskonen6Guillaume Romet-Lemonne7Pekka Lappalainen8Institute of Biotechnology and Helsinki Institute of Life Science, University of HelsinkiUniversité Paris Cité, CNRS, Institut Jacques MonodInstitute of Biotechnology and Helsinki Institute of Life Science, University of HelsinkiInstitute of Biotechnology and Helsinki Institute of Life Science, University of HelsinkiInstitute of Biotechnology and Helsinki Institute of Life Science, University of HelsinkiUniversité Paris Cité, CNRS, Institut Jacques MonodInstitute of Biotechnology and Helsinki Institute of Life Science, University of HelsinkiUniversité Paris Cité, CNRS, Institut Jacques MonodInstitute of Biotechnology and Helsinki Institute of Life Science, University of HelsinkiThe authors report here the structure-function analysis of highly divergent actin from Leishmania parasite. The study reveals remarkably rapid dynamics of parasite actin as well as the underlying molecular basis, thus providing insight into evolution of the actin cytoskeleton.https://doi.org/10.1038/s41467-022-31068-y |
| spellingShingle | Tommi Kotila Hugo Wioland Muniyandi Selvaraj Konstantin Kogan Lina Antenucci Antoine Jégou Juha T. Huiskonen Guillaume Romet-Lemonne Pekka Lappalainen Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite Nature Communications |
| title | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite |
| title_full | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite |
| title_fullStr | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite |
| title_full_unstemmed | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite |
| title_short | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite |
| title_sort | structural basis of rapid actin dynamics in the evolutionarily divergent leishmania parasite |
| url | https://doi.org/10.1038/s41467-022-31068-y |
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