Small protein sequences can induce cellular uptake of complex nanohybrids
In this letter, we report on the ability of functional fusion proteins presenting a lytic gamma peptide, to promote interactions with HeLa cells and delivery of large hybrid nanostructures.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
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Beilstein-Institut
2019-12-01
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Series: | Beilstein Journal of Nanotechnology |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjnano.10.238 |
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author | Jan-Philip Merkl Malak Safi Christian Schmidtke Fadi Aldeek Johannes Ostermann Tatiana Domitrovic Sebastian Gärtner John E. Johnson Horst Weller Hedi Mattoussi |
author_facet | Jan-Philip Merkl Malak Safi Christian Schmidtke Fadi Aldeek Johannes Ostermann Tatiana Domitrovic Sebastian Gärtner John E. Johnson Horst Weller Hedi Mattoussi |
author_sort | Jan-Philip Merkl |
collection | DOAJ |
description | In this letter, we report on the ability of functional fusion proteins presenting a lytic gamma peptide, to promote interactions with HeLa cells and delivery of large hybrid nanostructures. |
first_indexed | 2024-12-10T11:47:06Z |
format | Article |
id | doaj.art-b520b9a2a8fa40489d30c7564ad9fb33 |
institution | Directory Open Access Journal |
issn | 2190-4286 |
language | English |
last_indexed | 2024-12-10T11:47:06Z |
publishDate | 2019-12-01 |
publisher | Beilstein-Institut |
record_format | Article |
series | Beilstein Journal of Nanotechnology |
spelling | doaj.art-b520b9a2a8fa40489d30c7564ad9fb332022-12-22T01:50:03ZengBeilstein-InstitutBeilstein Journal of Nanotechnology2190-42862019-12-011012477248210.3762/bjnano.10.2382190-4286-10-238Small protein sequences can induce cellular uptake of complex nanohybridsJan-Philip Merkl0Malak Safi1Christian Schmidtke2Fadi Aldeek3Johannes Ostermann4Tatiana Domitrovic5Sebastian Gärtner6John E. Johnson7Horst Weller8Hedi Mattoussi9Department of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United StatesDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United StatesInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United StatesInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyInstituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro, 310. Lab I014, 21941-902, Rio de Janeiro, BrazilInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyThe Scripps Research Institute, Department of Integrative Structural and Computational Biology, MB31, La Jolla, California 92037, United StatesInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United StatesIn this letter, we report on the ability of functional fusion proteins presenting a lytic gamma peptide, to promote interactions with HeLa cells and delivery of large hybrid nanostructures.https://doi.org/10.3762/bjnano.10.238bioconjugationcellular uptakenanoparticle hybridspolymer encapsulationself-assembly |
spellingShingle | Jan-Philip Merkl Malak Safi Christian Schmidtke Fadi Aldeek Johannes Ostermann Tatiana Domitrovic Sebastian Gärtner John E. Johnson Horst Weller Hedi Mattoussi Small protein sequences can induce cellular uptake of complex nanohybrids Beilstein Journal of Nanotechnology bioconjugation cellular uptake nanoparticle hybrids polymer encapsulation self-assembly |
title | Small protein sequences can induce cellular uptake of complex nanohybrids |
title_full | Small protein sequences can induce cellular uptake of complex nanohybrids |
title_fullStr | Small protein sequences can induce cellular uptake of complex nanohybrids |
title_full_unstemmed | Small protein sequences can induce cellular uptake of complex nanohybrids |
title_short | Small protein sequences can induce cellular uptake of complex nanohybrids |
title_sort | small protein sequences can induce cellular uptake of complex nanohybrids |
topic | bioconjugation cellular uptake nanoparticle hybrids polymer encapsulation self-assembly |
url | https://doi.org/10.3762/bjnano.10.238 |
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