Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane

Targeting of the Gag polyprotein to the plasma membrane (PM) for assembly is a critical event in the late phase of immunodeficiency virus type-1 (HIV-1) infection. Gag binding to the PM is mediated by interactions between the myristoylated matrix (MA) domain and PM lipids. Despite the extensive bioc...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jiri eVlach, Jamil S Saad
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2015-03-01
سلاسل:Frontiers in Microbiology
الموضوعات:
الوصول للمادة أونلاين:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00232/full