Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane
Targeting of the Gag polyprotein to the plasma membrane (PM) for assembly is a critical event in the late phase of immunodeficiency virus type-1 (HIV-1) infection. Gag binding to the PM is mediated by interactions between the myristoylated matrix (MA) domain and PM lipids. Despite the extensive bioc...
| Главные авторы: | , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Frontiers Media S.A.
2015-03-01
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| Серии: | Frontiers in Microbiology |
| Предметы: | |
| Online-ссылка: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00232/full |