Infrequent p53 gene alterations in ulcerative colitis

The purpose of this study was to determine whether point mutations and loss of the p53 gene take place in ulcerative colitis which is histologically negative for dysplasia. DNA was extracted from 13 frozen rectal or colon biopsies and blood samples. Ulcerative colitis was classified histologically a...

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Bibliographic Details
Main Authors: R. Mattar, A.M. Alexandrino, A.A. Laudanna
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000900005