Expression of a Siglec-Fc Protein and Its Characterization

Expression of a Siglec-Fc Protein and Its Characterization

The emerging importance of the Siglec-sialic acid axis in human disease, especially cancer, has necessitated the identification of ligands for Siglecs. Recombinant Siglec-Fc fusion proteins have been widely used as ligand detectors, and also as sialic acid-targeted antibody-like proteins for cancer...

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Bibliographic Details
Main Authors: Kaijun Chi, Huilin Xu, Hanjie Li, Ganglong Yang, Xiaoman Zhou, Xiao-Dong Gao
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biology
Subjects:
sialic acid
Siglec-Fc
glycosylation
protein expression systems
Online Access:https://www.mdpi.com/2079-7737/12/4/574

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