Beyond Melanin: Proteomics Reveals Virulence-Related Proteins in <i>Paracoccidioides</i> <i>brasiliensis</i> and <i>Paracoccidioides</i> <i>lutzii</i> Yeast Cells Grown in the Presence of L-Dihydroxyphenylalanine

Beyond Melanin: Proteomics Reveals Virulence-Related Proteins in <i>Paracoccidioides</i> <i>brasiliensis</i> and <i>Paracoccidioides</i> <i>lutzii</i> Yeast Cells Grown in the Presence of L-Dihydroxyphenylalanine

Species of the genus <i>Paracoccidioides</i> cause a systemic infection in human patients. Yeast cells of <i>Paracoccidioides</i> spp. produce melanin in the presence of L-dihydroxyphenylalanine and during infection, which may impact the pathogen’s survival in the host. To be...

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Bibliographic Details
Main Authors: Rodrigo Almeida-Paes, Marcos Abreu Almeida, Lilian Cristiane Baeza, Leticia Andrade Mendes Marmello, Monique Ramos de Oliveira Trugilho, Joshua Daniel Nosanchuk, Celia Maria de Almeida Soares, Richard Hemmi Valente, Rosely Maria Zancopé-Oliveira
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Fungi
Subjects:
<i>Paracoccidioides</i>
melanin
L-dihydroxyphenylalanine
proteomics
metabolism
virulence
Online Access:https://www.mdpi.com/2309-608X/6/4/328

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