Mild Traumatic Brain Injury Induces Mitochondrial Calcium Overload and Triggers the Upregulation of NCLX in the Hippocampus
Traumatic brain injury (TBI) is brain damage due to external forces. Mild TBI (mTBI) is the most common form of TBI, and repeated mTBI is a risk factor for developing neurodegenerative diseases. Several mechanisms of neuronal damage have been described in the cortex and hippocampus, including mitoch...
Main Authors: | Rodrigo G. Mira, Rodrigo A. Quintanilla, Waldo Cerpa |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/12/2/403 |
Similar Items
-
CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca<sup>2+</sup> via Mitochondrial NCLX
by: Tomer Katoshevski, et al.
Published: (2022-12-01) -
NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition
by: Tie‐Gang Meng, et al.
Published: (2023-09-01) -
Physiological and Pathophysiological Roles of Mitochondrial Na<sup>+</sup>-Ca<sup>2+</sup> Exchanger, NCLX, in Hearts
by: Ayako Takeuchi, et al.
Published: (2021-12-01) -
Spatial and Functional Crosstalk between the Mitochondrial Na<sup>+</sup>-Ca<sup>2+</sup> Exchanger NCLX and the Sarcoplasmic Reticulum Ca<sup>2+</sup> Pump SERCA in Cardiomyocytes
by: Ayako Takeuchi, et al.
Published: (2022-07-01) -
Exo70 intracellular redistribution after repeated mild traumatic brain injury
by: Matías Lira, et al.
Published: (2021-02-01)