Combined In Silico and In Vitro Analyses to Assess the Anticancer Potential of Thiazolidinedione–Thiosemicarbazone Hybrid Molecules

Combined In Silico and In Vitro Analyses to Assess the Anticancer Potential of Thiazolidinedione–Thiosemicarbazone Hybrid Molecules

The number of people affected by cancer and antibiotic-resistant bacterial infections has increased, such that both diseases are already seen as current and future leading causes of death globally. To address this issue, based on a combined in silico and in vitro approach, we explored the anticancer...

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Bibliographic Details
Main Authors: Agata Paneth, Barbara Kaproń, Tomasz Plech, Roman Paduch, Nazar Trotsko, Piotr Paneth
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
thiazolidinedione
thiosemicarbazone
molecular docking
HDACs
PPARγ
cytotoxic effect
Online Access:https://www.mdpi.com/1422-0067/24/24/17521

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