INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE

Pharmacogenomics has the potential to improve patient-centered care and lead to an overall decrease in healthcare costs. This would be achieved through fewer hospitalizations due to adverse drug reactions, individualized and effective therapies, and decreased drug development costs with single nucle...

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Main Authors: Gurinder Johal, Adam Amlani
Format: Article
Language:English
Published: University of Ottawa 2016-05-01
Series:University of Ottawa Journal of Medicine
Subjects:
Online Access:https://uottawa.scholarsportal.info/ottawa/index.php/uojm-jmuo/article/view/1549
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author Gurinder Johal
Adam Amlani
author_facet Gurinder Johal
Adam Amlani
author_sort Gurinder Johal
collection DOAJ
description Pharmacogenomics has the potential to improve patient-centered care and lead to an overall decrease in healthcare costs. This would be achieved through fewer hospitalizations due to adverse drug reactions, individualized and effective therapies, and decreased drug development costs with single nucleotide polymorphism pre-screening. Although challenges do exist in encouraging the use of phar­macogenomics―specifically in regards to resources, regulation, and impacts on the pharmaceutical industry―the benefits may out­weigh the costs in terms of patient health and safety. In implementing pharmacogenomics, various clinical, ethical, legal, social and economical factors must be considered.   La pharmacogénomique aurait le potentiel de diminuer le coût des soins de santé et d’optimiser les soins primaires aux patients. Il serait possible d’y parvenir en réduisant les hospitalisations suite aux effets secondaires associés aux médicaments, en utilisant des thérapies individualisées plus efficaces et en diminuant le coût associé au développement de médicaments grâce au test de dépistage de polymorphisme d’un seul nucléotide. Malgré les défis associés à l’utilisation de la pharmacogénomique surtout sur le plan des ressources, de la régulation et de l’impact dans l’industrie pharmaceutique, les avantages en terme de santé et de sécurité sont à considérer. Plusieurs facteurs cliniques, éthiques, légaux, sociaux, et économiques doivent être pris en considération pour l’utilisation de la pharmacogénomique.
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spelling doaj.art-b539cbc7b87f45a29bef8248a69718062022-12-22T02:46:27ZengUniversity of OttawaUniversity of Ottawa Journal of Medicine2292-650X2292-65182016-05-016110.18192/uojm.v6i1.1549INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICEGurinder Johal0Adam Amlani1University of British ColumbiaUniversity of British ColumbiaPharmacogenomics has the potential to improve patient-centered care and lead to an overall decrease in healthcare costs. This would be achieved through fewer hospitalizations due to adverse drug reactions, individualized and effective therapies, and decreased drug development costs with single nucleotide polymorphism pre-screening. Although challenges do exist in encouraging the use of phar­macogenomics―specifically in regards to resources, regulation, and impacts on the pharmaceutical industry―the benefits may out­weigh the costs in terms of patient health and safety. In implementing pharmacogenomics, various clinical, ethical, legal, social and economical factors must be considered.   La pharmacogénomique aurait le potentiel de diminuer le coût des soins de santé et d’optimiser les soins primaires aux patients. Il serait possible d’y parvenir en réduisant les hospitalisations suite aux effets secondaires associés aux médicaments, en utilisant des thérapies individualisées plus efficaces et en diminuant le coût associé au développement de médicaments grâce au test de dépistage de polymorphisme d’un seul nucléotide. Malgré les défis associés à l’utilisation de la pharmacogénomique surtout sur le plan des ressources, de la régulation et de l’impact dans l’industrie pharmaceutique, les avantages en terme de santé et de sécurité sont à considérer. Plusieurs facteurs cliniques, éthiques, légaux, sociaux, et économiques doivent être pris en considération pour l’utilisation de la pharmacogénomique.https://uottawa.scholarsportal.info/ottawa/index.php/uojm-jmuo/article/view/1549PharmacogenomicsPharmacogenetics
spellingShingle Gurinder Johal
Adam Amlani
INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
University of Ottawa Journal of Medicine
Pharmacogenomics
Pharmacogenetics
title INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
title_full INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
title_fullStr INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
title_full_unstemmed INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
title_short INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
title_sort integrating pharmacogenomics into clinical practice
topic Pharmacogenomics
Pharmacogenetics
url https://uottawa.scholarsportal.info/ottawa/index.php/uojm-jmuo/article/view/1549
work_keys_str_mv AT gurinderjohal integratingpharmacogenomicsintoclinicalpractice
AT adamamlani integratingpharmacogenomicsintoclinicalpractice