| Summary: | The increase in bacterial resistance to one or several antibiotics has become a global health problem. Nanocomposites have become a tool against multidrug-resistant bacteria. A nanocomposite, Ag<sub>2</sub>O/SrO/CaO, was prepared from AgNO<sub>3</sub>, SrCl<sub>2</sub>·6H<sub>2</sub>O, CaCl<sub>2</sub>, and a solution of Na<sub>2</sub>CO<sub>3</sub> via the calcination of the salts mixture. The nanocomposite was successfully prepared by the co-precipitation method and completely according to green chemistry, in terms of synthesis method, solvent and precursors. The nanocomposite was characterized by XRD, XRF, and FESEM analyses. Afterwards, the nanocomposite was applied for antibacterial activity against gram-positive and gram-negative bacteria including PS Aeruginosa, Keleb peneumonia, Staph coccus aureus, Staph sapropphyticus, and Escherichia coli.
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