S1R agonist modulates rat platelet eicosanoid synthesis and aggregation
Sigma-1 receptor (S1R) is detected in different cell types and can regulate intracellular signaling pathways. S1R plays a role in the pathomechanism of diseases and the regulation of neurotransmitters. Fluvoxamine can bind to S1R and reduce the serotonin uptake of neurons and platelets. We therefore...
Main Authors: | Sándor Váczi, L. Barna, A. Harazin, M. Mészáros, G. Porkoláb, Á. Zvara, R. Ónody, I. Földesi, S. Veszelka, B. Penke, L. Fülöp, M. A. Deli, Z. Mezei |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-07-01
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Series: | Platelets |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/09537104.2021.1981843 |
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