SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods
The detection of hydrogen peroxide and the control of its concentration are important tasks in the biological and chemical sciences. In this paper, we developed a simple and quantitative method for the non-enzymatic detection of H<sub>2</sub>O<sub>2</sub> based on the selecti...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/22/9/3202 |
| _version_ | 1797502935953833984 |
|---|---|
| author | Boris N. Khlebtsov Andrey M. Burov Andrey M. Zakharevich Nikolai G. Khlebtsov |
| author_facet | Boris N. Khlebtsov Andrey M. Burov Andrey M. Zakharevich Nikolai G. Khlebtsov |
| author_sort | Boris N. Khlebtsov |
| collection | DOAJ |
| description | The detection of hydrogen peroxide and the control of its concentration are important tasks in the biological and chemical sciences. In this paper, we developed a simple and quantitative method for the non-enzymatic detection of H<sub>2</sub>O<sub>2</sub> based on the selective etching of Au@Ag nanorods with embedded Raman active molecules. The transfer of electrons between silver atoms and hydrogen peroxide enhances the oxidation reaction, and the Ag shell around the Au nanorod gradually dissolves. This leads to a change in the color of the nanoparticle colloid, a shift in LSPR, and a decrease in the SERS response from molecules embedded between the Au core and Ag shell. In our study, we compared the sensitivity of these readouts for nanoparticles with different Ag shell morphology. We found that triangle core–shell nanoparticles exhibited the highest sensitivity, with a detection limit of 10<sup>−4</sup> M, and the SERS detection range of 1 × 10<sup>−4</sup> to 2 × 10<sup>−2</sup> M. In addition, a colorimetric strategy was applied to fabricate a simple indicator paper sensor for fast detection of hydrogen peroxide in liquids. In this case, the concentration of hydrogen peroxide was qualitatively determined by the change in the color of the nanoparticles deposited on the nitrocellulose membrane. |
| first_indexed | 2024-03-10T03:43:17Z |
| format | Article |
| id | doaj.art-b5551aebf3ee4f7daed047a1a5adabb0 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T03:43:17Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-b5551aebf3ee4f7daed047a1a5adabb02023-11-23T09:14:54ZengMDPI AGSensors1424-82202022-04-01229320210.3390/s22093202SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag NanorodsBoris N. Khlebtsov0Andrey M. Burov1Andrey M. Zakharevich2Nikolai G. Khlebtsov3Institute of Biochemistry and Physiology of Plants and Microorganisms, Saratov Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), 410049 Saratov, RussiaInstitute of Biochemistry and Physiology of Plants and Microorganisms, Saratov Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), 410049 Saratov, RussiaDepartment of Physics, Saratov State University, 410012 Saratov, RussiaInstitute of Biochemistry and Physiology of Plants and Microorganisms, Saratov Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), 410049 Saratov, RussiaThe detection of hydrogen peroxide and the control of its concentration are important tasks in the biological and chemical sciences. In this paper, we developed a simple and quantitative method for the non-enzymatic detection of H<sub>2</sub>O<sub>2</sub> based on the selective etching of Au@Ag nanorods with embedded Raman active molecules. The transfer of electrons between silver atoms and hydrogen peroxide enhances the oxidation reaction, and the Ag shell around the Au nanorod gradually dissolves. This leads to a change in the color of the nanoparticle colloid, a shift in LSPR, and a decrease in the SERS response from molecules embedded between the Au core and Ag shell. In our study, we compared the sensitivity of these readouts for nanoparticles with different Ag shell morphology. We found that triangle core–shell nanoparticles exhibited the highest sensitivity, with a detection limit of 10<sup>−4</sup> M, and the SERS detection range of 1 × 10<sup>−4</sup> to 2 × 10<sup>−2</sup> M. In addition, a colorimetric strategy was applied to fabricate a simple indicator paper sensor for fast detection of hydrogen peroxide in liquids. In this case, the concentration of hydrogen peroxide was qualitatively determined by the change in the color of the nanoparticles deposited on the nitrocellulose membrane.https://www.mdpi.com/1424-8220/22/9/3202hydrogen peroxideAu@Ag nanorodsetchingSERS |
| spellingShingle | Boris N. Khlebtsov Andrey M. Burov Andrey M. Zakharevich Nikolai G. Khlebtsov SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods Sensors hydrogen peroxide Au@Ag nanorods etching SERS |
| title | SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods |
| title_full | SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods |
| title_fullStr | SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods |
| title_full_unstemmed | SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods |
| title_short | SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods |
| title_sort | sers and indicator paper sensing of hydrogen peroxide using au ag nanorods |
| topic | hydrogen peroxide Au@Ag nanorods etching SERS |
| url | https://www.mdpi.com/1424-8220/22/9/3202 |
| work_keys_str_mv | AT borisnkhlebtsov sersandindicatorpapersensingofhydrogenperoxideusingauagnanorods AT andreymburov sersandindicatorpapersensingofhydrogenperoxideusingauagnanorods AT andreymzakharevich sersandindicatorpapersensingofhydrogenperoxideusingauagnanorods AT nikolaigkhlebtsov sersandindicatorpapersensingofhydrogenperoxideusingauagnanorods |