Inflammatory Cytokines Alter Mesenchymal Stem Cell Mechanosensing and Adhesion on Stiffened Infarct Heart Tissue After Myocardial Infarction
Mesenchymal stem cell (MSC) transplantation has demonstrated its potential in repairing infarct heart tissue and recovering heart function after myocardial infarction (MI). However, its therapeutic effect is still limited due to poor MSC engraftment at the injury site whose tissue stiffness and loca...
Main Authors: | Dan Zhu, Peng Wu, Changchen Xiao, Wei Hu, Tongtong Zhang, Xinyang Hu, Wei Chen, Jian’an Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-10-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2020.583700/full |
Similar Items
-
Compression stiffening of brain and its effect on mechanosensing by glioma cells
by: Katarzyna Pogoda, et al.
Published: (2014-01-01) -
TRPV Protein Family—From Mechanosensing to Cancer Invasion
by: Tytti Kärki, et al.
Published: (2021-07-01) -
Distinct roles for innexin gap junctions and hemichannels in mechanosensation
by: Denise S Walker, et al.
Published: (2020-01-01) -
Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
by: Chinky Shiu Chen Liu, et al.
Published: (2024-02-01) -
Harnessing Mechanosensation in Next Generation Cardiovascular Tissue Engineering
by: Gloria Garoffolo, et al.
Published: (2020-10-01)