Electrospun PLGA Fiber Diameter and Alignment of Tendon Biomimetic Fleece Potentiate Tenogenic Differentiation and Immunomodulatory Function of Amniotic Epithelial Stem Cells

Electrospun PLGA Fiber Diameter and Alignment of Tendon Biomimetic Fleece Potentiate Tenogenic Differentiation and Immunomodulatory Function of Amniotic Epithelial Stem Cells

Injured tendons are challenging in their regeneration; thus, tissue engineering represents a promising solution. This research tests the hypothesis that the response of amniotic epithelial stem cells (AECs) can be modulated by fiber diameter size of tendon biomimetic fleeces. Particularly, the effec...

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Bibliographic Details
Main Authors: Mohammad El Khatib, Annunziata Mauro, Miriam Di Mattia, Ralf Wyrwa, Martina Schweder, Massimo Ancora, Francesco Lazzaro, Paolo Berardinelli, Luca Valbonetti, Oriana Di Giacinto, Andrea Polci, Cesare Cammà, Matthias Schnabelrauch, Barbara Barboni, Valentina Russo
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
tendon
amniotic epithelial stem cells
fiber diameter size
aligned fibers
tendon tissue engineering
PLGA
Online Access:https://www.mdpi.com/2073-4409/9/5/1207

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