Integrative Analysis of Gut Microbiota and Fecal Metabolites in Rats after Prednisone Treatment

Integrative Analysis of Gut Microbiota and Fecal Metabolites in Rats after Prednisone Treatment

ABSTRACT Prednisone (PRED) is a synthetic glucocorticoid (GC) widely used in immune-mediated diseases for its immunosuppressive and anti-inflammatory properties. The effects of GC are achieved by genomic and nongenomic mechanisms. However, the nongenomic effects are largely unknown. Thus, we aimed t...

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Bibliographic Details
Main Authors: Jing Zhang, Dan Feng, Helen Ka-Wai Law, Ying Wu, Guang-hua Zhu, Wen-yan Huang, Yulin Kang
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:Microbiology Spectrum
Subjects:
prednisone
gut microbiota
fecal metabolite
short-chain fatty acid
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00650-21

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