Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction

Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction

IntroductionP2X receptors are a family of homo- and heterotrimeric cation channels gated by extracellular ATP. The P2X4 and P2X7 subunits show overlapping expression patterns and have been involved in similar physiological processes, such as pain and inflammation as well as various immune cell funct...

Полное описание

Библиографические подробности
Главные авторы:	Juan Sierra-Marquez, Lena Schaller, Lukas Sassenbach, Antonio Ramírez-Fernández, Philipp Alt, Björn Rissiek, Béla Zimmer, Johann Schredelseker, Julia Hector, Tobias Stähler, Friedrich Koch-Nolte, Claudia A. Staab-Weijnitz, Alexander Dietrich, Robin Kopp, Annette Nicke
Формат:	Статья
Язык:	English
Опубликовано:	Frontiers Media S.A. 2024-06-01
Серии:	Frontiers in Immunology
Предметы:	P2X7 receptor P2X4 receptor heteromerization functional interaction lung epithelial cells macrophage
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1425938/full

Схожие документы

Interaction of Purinergic P2X4 and P2X7 Receptor Subunits
по: Markus Schneider, и др.
Опубликовано: (2017-11-01)

Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors
по: Joelyn Wong, и др.
Опубликовано: (2022-05-01)

P2X7 receptor in inflammation and pain
по: Shi-qi Hu, и др.
Опубликовано: (2022-09-01)

P2X7 Receptor in Hematological Malignancies
по: Elena De Marchi, и др.
Опубликовано: (2021-03-01)

Research progress on P2X7 receptor in cancer pain
по: ZHANG Zhongwen, ZHAO Rui, ZHANG Haolong, YANG Yuting, BAI Jinxia, ZHANG Haoling WANG Wei
Опубликовано: (2024-03-01)

The P2X7 Receptor: Central Hub of Brain Diseases
по: Roberta Andrejew, и др.
Опубликовано: (2020-07-01)

Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective
по: Jean M. Kanellopoulos, и др.
Опубликовано: (2021-03-01)

6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist
по: Peter Cuthbertson, и др.
Опубликовано: (2022-09-01)

P2X4: A fast and sensitive purinergic receptor
по: Jaanus Suurväli, и др.
Опубликовано: (2017-10-01)

P2X and P2Y receptor signaling in red blood cells
по: Ronald eSluyter, и др.
Опубликовано: (2015-10-01)

P2X7 Receptors in Astrocytes: A Switch for Ischemic Tolerance
по: Yuri Hirayama, и др.
Опубликовано: (2022-06-01)

Role of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation “in vivo” by P2X7 receptor
по: M. Teresa Miras-Portugal, и др.
Опубликовано: (2015-01-01)

Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
по: Karina Kaczmarek-Hajek, и др.
Опубликовано: (2018-08-01)

Cancer Metabostemness and Metabolic Reprogramming via P2X7 Receptor
по: Izadora Lorrany Alves Rabelo, и др.
Опубликовано: (2021-07-01)

P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders
по: Kelle M. Franklin, и др.
Опубликовано: (2014-06-01)

The P2X7 receptor is an important regulator of extracellular ATP levels
по: Andrea eBrandao-Burch, и др.
Опубликовано: (2012-03-01)

The role of p2x7 receptor in infectious inflammatory diseases and the influence of ectonucleotidases
по: Ana Carolina Morandini, и др.
Опубликовано: (2014-08-01)

P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications
по: Andrea Spinaci, и др.
Опубликовано: (2021-04-01)

Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats
по: Robert I Menzies, и др.
Опубликовано: (2013-10-01)

P2X7 Receptor–Mediated Inflammation in Cardiovascular Disease
по: Junteng Zhou, и др.
Опубликовано: (2021-04-01)

P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes
по: Jiratchaya Srisutha, и др.
Опубликовано: (2024-05-01)

Role and therapeutic targets of P2X7 receptors in neurodegenerative diseases
по: Huiyong Zheng, и др.
Опубликовано: (2024-02-01)

Structural basis for subtype-specific inhibition of the P2X7 receptor
по: Akira Karasawa, и др.
Опубликовано: (2016-12-01)

P2X7 receptors in satellite glial cells mediate high functional expression of P2X3 receptors in immature dorsal root ganglion neurons
по: Chen Yong, и др.
Опубликовано: (2012-02-01)

Emerging key roles for P2X receptors in the kidney
по: Scott S Wildman
Опубликовано: (2013-09-01)

P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis
по: Alazne Zabala, и др.
Опубликовано: (2018-07-01)

Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors
по: Irena Svobodova, и др.
Опубликовано: (2018-03-01)

P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer’s disease
по: Carolina Bianchi, и др.
Опубликовано: (2023-06-01)

The relationship between P2X4 and P2X7: a physiologically important interaction?
по: Eilidh eCraigie, и др.
Опубликовано: (2013-08-01)

Role of P2X7 receptor in the progression and clinicopathological characteristics of gastric cancer
по: Wen-jun Zhang, и др.
Опубликовано: (2024-12-01)

Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel
по: Waldemar Schäfer, и др.
Опубликовано: (2022-11-01)

P2X1 receptors and the endothelium
по: LS Harrington, и др.
Опубликовано: (2005-03-01)

P2X7 Variants in Oncogenesis
по: Anna Pegoraro, и др.
Опубликовано: (2021-01-01)

Spinal cannabinoid receptor 2 activation alleviates neuropathic pain by regulating microglia and suppressing P2X7 receptor
по: Yifan Zhou, и др.
Опубликовано: (2023-03-01)

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family
по: Xiao-Bo Ma, и др.
Опубликовано: (2024-12-01)

P2X7 Receptor Antagonism as a Potential Therapy in Amyotrophic Lateral Sclerosis
по: Cristina Ruiz-Ruiz, и др.
Опубликовано: (2020-06-01)

P2x7 receptors control demyelination and inflammation in the cuprizone model
по: Ana Bernal-Chico, и др.
Опубликовано: (2020-04-01)

Exploring the Role of P2X Receptors in Alzheimer’s Disease
по: Pamela Andrea Godoy, и др.
Опубликовано: (2019-11-01)

To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?
по: Leanne Stokes, и др.
Опубликовано: (2020-05-01)

Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions
по: Maximilian Wilmes, и др.
Опубликовано: (2022-10-01)