A Polymorphism in C-C Chemokine Receptor 5 (CCR5) Associates with Löfgren’s Syndrome and Alters Receptor Expression as well as Functional Response

A Polymorphism in C-C Chemokine Receptor 5 (CCR5) Associates with Löfgren’s Syndrome and Alters Receptor Expression as well as Functional Response

C-C chemokine receptor 5 (CCR5) and polymorphisms in <i>CCR5</i> gene are associated with sarcoidosis and Löfgren’s syndrome. Löfgren’s syndrome is an acute and usually self-remitting phenotype of sarcoidosis. We investigated whether the single nucleotide polymorphism (SNP) rs1799987 is...

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Bibliographic Details
Main Authors: Bekir Karakaya, Coline H. M. van Moorsel, Marcel Veltkamp, Claudia Roodenburg-Benschop, Karin M. Kazemier, Annette H. M. van der Helm-van Mil, Tom W. J. Huizinga, Jan C. Grutters, Ger T. Rijkers
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
sarcoidosis
Löfgren’s syndrome
C-C chemokine receptor 5 (CCR5)
calcium influx
calcium kinetics
single nucleotide polymorphism (SNP)
Online Access:https://www.mdpi.com/2073-4409/10/8/1967

Internet

https://www.mdpi.com/2073-4409/10/8/1967

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