A High-Throughput Method for Identifying Novel Genes That Influence Metabolic Pathways Reveals New Iron and Heme Regulation in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>

A High-Throughput Method for Identifying Novel Genes That Influence Metabolic Pathways Reveals New Iron and Heme Regulation in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>

ABSTRACT Heme is an essential metabolite for most life on earth. Bacterial pathogens almost universally require iron to infect a host, often acquiring this nutrient in the form of heme. The Gram-negative pathogen Pseudomonas aeruginosa is no exception, where heme acquisition and metabolism are known...

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Bibliographic Details
Main Authors: David G. Glanville, Caroline Mullineaux-Sanders, Christopher J. Corcoran, Brian T. Burger, Saheed Imam, Timothy J. Donohue, Andrew T. Ulijasz
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSystems
Subjects:
Pseudomonas aeruginosa
Tn-seq
biosensor
heme
heme biosynthesis
heme transport
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00933-20

Internet

https://journals.asm.org/doi/10.1128/mSystems.00933-20

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