Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study

Background: Varicocele is present in up to 19­–41% of men with primary infertility and 80% of men with secondary infertility. Varicocele is associated with abnormal semen parameters. The role of platelet indices [PIs] in many vascular diseases, including varicocele, has been widely studied.Aim of th...

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Main Authors: Mohamed Ahmed, Mohamed Kamel, AbdElaleem Elgendy
Format: Article
Language:English
Published: Al-Azhar University, Faculty of Medicine (Damietta) 2023-10-01
Series:International Journal of Medical Arts
Subjects:
Online Access:https://ijma.journals.ekb.eg/article_327863_8ed59c68622bd0a464162e25510f463d.pdf
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author Mohamed Ahmed
Mohamed Kamel
AbdElaleem Elgendy
author_facet Mohamed Ahmed
Mohamed Kamel
AbdElaleem Elgendy
author_sort Mohamed Ahmed
collection DOAJ
description Background: Varicocele is present in up to 19­–41% of men with primary infertility and 80% of men with secondary infertility. Varicocele is associated with abnormal semen parameters. The role of platelet indices [PIs] in many vascular diseases, including varicocele, has been widely studied.Aim of the Study: The aim of this study was to evaluate the platelet indices in varicocele patients and its value in association with abnormal semen parameters.Patients and Methods: A cross sectional study was conducted on 122 male patients with varicocele, recruited from Dermatology, Venereology & Andrology Outpatient Clinics in Al-Azhar University Hospitals, Cairo, Egypt. The patients were classified into two groups [61 patients with varicocele associated with normal semen parameters and 61 patients with varicocele associated with abnormal semen parameters]. All patients were subjected to history taking, general and genital examination, complete blood count [CBC] and Scrotal Doppler Ultrasound. PIs were then compared between the two groups by their characteristics and grade of varicocele using appropriate statistical tests.Results: Of the studied platelet indices, the mean platelet volume [MPV] and plateletcrit [PCT] were significantly higher in varicocele group associated with abnormal semen parameters compared to varicocele group associated with normal semen parameters [9.5 ± 1.4 vs. to 7.9 ± 0.98; and 0.22 ± 0.05 vs. 0.18 ± 0.04]. In the varicocele group associated with abnormal semen parameters, the mean PCT and platelet distribution width [PDW] were significantly higher in the studied varicocele grades II and III compared to grade I. A significant moderate positive correlation was found between MPV and PCT and the number of sperms in the varicocele group associated with abnormal semen parameters.Conclusion: The study findings indicating that MPV and PCT were significantly higher in Varicocele patients with abnormal semen parameters than in normospermic varicocele patients.
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spelling doaj.art-b561f6e4d36e43059a3a8f0a92bff3be2024-01-05T19:32:49ZengAl-Azhar University, Faculty of Medicine (Damietta)International Journal of Medical Arts2636-41742682-37802023-10-015103682368610.21608/ijma.2023.238566.1821327863Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional StudyMohamed Ahmed0Mohamed Kamel1AbdElaleem Elgendy2Department of Dermatology, Venereology and Andrology, The Egyptian Ministry of Health, Cairo, EgyptDepartment of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Cairo, EgyptDepartment of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, EgyptBackground: Varicocele is present in up to 19­–41% of men with primary infertility and 80% of men with secondary infertility. Varicocele is associated with abnormal semen parameters. The role of platelet indices [PIs] in many vascular diseases, including varicocele, has been widely studied.Aim of the Study: The aim of this study was to evaluate the platelet indices in varicocele patients and its value in association with abnormal semen parameters.Patients and Methods: A cross sectional study was conducted on 122 male patients with varicocele, recruited from Dermatology, Venereology & Andrology Outpatient Clinics in Al-Azhar University Hospitals, Cairo, Egypt. The patients were classified into two groups [61 patients with varicocele associated with normal semen parameters and 61 patients with varicocele associated with abnormal semen parameters]. All patients were subjected to history taking, general and genital examination, complete blood count [CBC] and Scrotal Doppler Ultrasound. PIs were then compared between the two groups by their characteristics and grade of varicocele using appropriate statistical tests.Results: Of the studied platelet indices, the mean platelet volume [MPV] and plateletcrit [PCT] were significantly higher in varicocele group associated with abnormal semen parameters compared to varicocele group associated with normal semen parameters [9.5 ± 1.4 vs. to 7.9 ± 0.98; and 0.22 ± 0.05 vs. 0.18 ± 0.04]. In the varicocele group associated with abnormal semen parameters, the mean PCT and platelet distribution width [PDW] were significantly higher in the studied varicocele grades II and III compared to grade I. A significant moderate positive correlation was found between MPV and PCT and the number of sperms in the varicocele group associated with abnormal semen parameters.Conclusion: The study findings indicating that MPV and PCT were significantly higher in Varicocele patients with abnormal semen parameters than in normospermic varicocele patients.https://ijma.journals.ekb.eg/article_327863_8ed59c68622bd0a464162e25510f463d.pdfplateletsplatelet indicesmean platelet volumevaricocelesemen
spellingShingle Mohamed Ahmed
Mohamed Kamel
AbdElaleem Elgendy
Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study
International Journal of Medical Arts
platelets
platelet indices
mean platelet volume
varicocele
semen
title Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study
title_full Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study
title_fullStr Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study
title_full_unstemmed Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study
title_short Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study
title_sort value of platelet indices in evaluation of varicocele patients and its associated abnormal semen parameters a cross sectional study
topic platelets
platelet indices
mean platelet volume
varicocele
semen
url https://ijma.journals.ekb.eg/article_327863_8ed59c68622bd0a464162e25510f463d.pdf
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AT abdelaleemelgendy valueofplateletindicesinevaluationofvaricocelepatientsanditsassociatedabnormalsemenparametersacrosssectionalstudy