Potential Pharmacokinetic Effect of Chicken Xenobiotic Receptor Activator on Sulfadiazine: Involvement of P-glycoprotein Induction

Potential Pharmacokinetic Effect of Chicken Xenobiotic Receptor Activator on Sulfadiazine: Involvement of P-glycoprotein Induction

Studies on pharmacokinetic drug–drug interactions have highlighted the importance of P-glycoprotein (P-gp) because of its involvement in substrate drug transport. This study aimed to investigate the role of chicken xenobiotic receptor (CXR) in the regulation of P-gp and its influences on pharmacokin...

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Bibliographic Details
Main Authors: Mei Li, Ziyong Xu, Wang Lu, Liping Wang, Yujuan Zhang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antibiotics
Subjects:
P-gp
induction
sulfadiazine
CXR
chickens
Online Access:https://www.mdpi.com/2079-6382/11/8/1005

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