Intestinal group 1 innate lymphoid cells drive macrophage-induced inflammation and endocrine defects in obesity and promote insulinemia

Intestinal group 1 innate lymphoid cells drive macrophage-induced inflammation and endocrine defects in obesity and promote insulinemia

ABSTRACTHypercaloric diets overactivate the intestinal immune system and disrupt the microbiome and epithelial cell functions, impairing glucose metabolism. The origins of this inflammatory cascade are poorly characterized. We investigated the involvement of intestinal proinflammatory group 1 innate...

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Bibliographic Details
Main Authors: Rebeca Liébana-García, Marta Olivares, Carlos Francés-Cuesta, Teresa Rubio, Valerio Rossini, Guillermo Quintas, Yolanda Sanz
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Microbiota
obesity
ILC1s
metabolism
high-sucrose high-fat diet
Akkermansia muciniphila
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2181928

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