Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report

We report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging...

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Main Authors: Hiromichi Katayama, Hiroshi Aoki, Katsuyuki Taguchi, Yuu Sakurada, Tomonori Sato, Masahiro Takahashi, Rie Shibuya, Hiroshi Naganuma, Shigeto Ishidoya
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442016301012
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author Hiromichi Katayama
Hiroshi Aoki
Katsuyuki Taguchi
Yuu Sakurada
Tomonori Sato
Masahiro Takahashi
Rie Shibuya
Hiroshi Naganuma
Shigeto Ishidoya
author_facet Hiromichi Katayama
Hiroshi Aoki
Katsuyuki Taguchi
Yuu Sakurada
Tomonori Sato
Masahiro Takahashi
Rie Shibuya
Hiroshi Naganuma
Shigeto Ishidoya
author_sort Hiromichi Katayama
collection DOAJ
description We report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging showed heterogeneous tumor without any metastatic lesions. We conducted 4 courses of chemotherapy before detecting hCG nadir. The final pathological report showed pure seminoma with syncytiotrophoblastic cells but no choriocarcinoma components. The patient remains disease free until present time. The case raised several questions regarding diagnosis and treatment strategy for bulky testicular seminoma.
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spelling doaj.art-b5645a046ec1462b903baad5661bdbb02022-12-22T01:59:13ZengElsevierUrology Case Reports2214-44202016-11-019C485010.1016/j.eucr.2016.08.012Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case ReportHiromichi Katayama0Hiroshi Aoki1Katsuyuki Taguchi2Yuu Sakurada3Tomonori Sato4Masahiro Takahashi5Rie Shibuya6Hiroshi Naganuma7Shigeto Ishidoya8Division of Urology, Sendai City Hospital, Sendai, JapanDivision of Urology, Sendai City Hospital, Sendai, JapanDivision of Urology, Sendai City Hospital, Sendai, JapanDivision of Urology, Sendai City Hospital, Sendai, JapanDivision of Urology, Sendai City Hospital, Sendai, JapanDivision of Urology, Sendai City Hospital, Sendai, JapanDivision of Pathology, Sendai City Hospital, Sendai, JapanDivision of Pathology, Sendai City Hospital, Sendai, JapanDivision of Urology, Sendai City Hospital, Sendai, JapanWe report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging showed heterogeneous tumor without any metastatic lesions. We conducted 4 courses of chemotherapy before detecting hCG nadir. The final pathological report showed pure seminoma with syncytiotrophoblastic cells but no choriocarcinoma components. The patient remains disease free until present time. The case raised several questions regarding diagnosis and treatment strategy for bulky testicular seminoma.http://www.sciencedirect.com/science/article/pii/S2214442016301012SeminomahCGSyncytiotrophoblastic cells
spellingShingle Hiromichi Katayama
Hiroshi Aoki
Katsuyuki Taguchi
Yuu Sakurada
Tomonori Sato
Masahiro Takahashi
Rie Shibuya
Hiroshi Naganuma
Shigeto Ishidoya
Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report
Urology Case Reports
Seminoma
hCG
Syncytiotrophoblastic cells
title Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report
title_full Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report
title_fullStr Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report
title_full_unstemmed Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report
title_short Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report
title_sort pure stage i seminoma with an elevated hcg of 25 265 miu ml a case report
topic Seminoma
hCG
Syncytiotrophoblastic cells
url http://www.sciencedirect.com/science/article/pii/S2214442016301012
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