Covid-19 infection in pregnant women in Dubai: a case-control study
Abstract Background Whilst the impact of Covid-19 infection in pregnant women has been examined, there is a scarcity of data on pregnant women in the Middle East. Thus, the aim of this study was to examine the impact of Covid-19 infection on pregnant women in the United Arab Emirates population. Met...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-09-01
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| Series: | BMC Pregnancy and Childbirth |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12884-021-04130-8 |
| _version_ | 1818986757649072128 |
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| author | Komal Sundeep Hazari Rasha Abdeldayem Litty Paulose Nimmi Kurien Zukaa Almahloul Hozaifah Mohammad Taghrid Faek A. Elgergawi Maryam Alkhanbouli Khalid Mahmoud Atif Bashir Fazari Amar Hassan Riad Bayoumi |
| author_facet | Komal Sundeep Hazari Rasha Abdeldayem Litty Paulose Nimmi Kurien Zukaa Almahloul Hozaifah Mohammad Taghrid Faek A. Elgergawi Maryam Alkhanbouli Khalid Mahmoud Atif Bashir Fazari Amar Hassan Riad Bayoumi |
| author_sort | Komal Sundeep Hazari |
| collection | DOAJ |
| description | Abstract Background Whilst the impact of Covid-19 infection in pregnant women has been examined, there is a scarcity of data on pregnant women in the Middle East. Thus, the aim of this study was to examine the impact of Covid-19 infection on pregnant women in the United Arab Emirates population. Methods A case-control study was carried out to compare the clinical course and outcome of pregnancy in 79 pregnant women with Covid-19 and 85 non-pregnant women with Covid-19 admitted to Latifa Hospital in Dubai between March and June 2020. Results Although Pregnant women presented with fewer symptoms such as fever, cough, sore throat, and shortness of breath compared to non-pregnant women; yet they ran a much more severe course of illness. On admission, 12/79 (15.2%) Vs 2/85 (2.4%) had a chest radiograph score [on a scale 1-6] of ≥3 (p-value = 0.0039). On discharge, 6/79 (7.6%) Vs 1/85 (1.2%) had a score ≥3 (p-value = 0.0438). They also had much higher levels of laboratory indicators of severity with values above reference ranges for C-Reactive Protein [(28 (38.3%) Vs 13 (17.6%)] with p < 0.004; and for D-dimer [32 (50.8%) Vs 3(6%)]; with p < 0.001. They required more ICU admissions: 10/79 (12.6%) Vs 1/85 (1.2%) with p=0.0036; and suffered more complications: 9/79 (11.4%) Vs 1/85 (1.2%) with p=0.0066; of Covid-19 infection, particularly in late pregnancy. Conclusions Pregnant women presented with fewer Covid-19 symptoms but ran a much more severe course of illness compared to non-pregnant women with the disease. They had worse chest radiograph scores and much higher levels of laboratory indicators of disease severity. They had more ICU admissions and suffered more complications of Covid-19 infection, such as risk for miscarriage and preterm deliveries. Pregnancy with Covid-19 infection, could, therefore, be categorised as high-risk pregnancy and requires management by an obstetric and medical multidisciplinary team. |
| first_indexed | 2024-12-20T18:55:52Z |
| format | Article |
| id | doaj.art-b5683de8df28417c9d1197a344784e6a |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-20T18:55:52Z |
| publishDate | 2021-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-b5683de8df28417c9d1197a344784e6a2022-12-21T19:29:31ZengBMCBMC Pregnancy and Childbirth1471-23932021-09-0121111010.1186/s12884-021-04130-8Covid-19 infection in pregnant women in Dubai: a case-control studyKomal Sundeep Hazari0Rasha Abdeldayem1Litty Paulose2Nimmi Kurien3Zukaa Almahloul4Hozaifah Mohammad5Taghrid Faek A. Elgergawi6Maryam Alkhanbouli7Khalid Mahmoud8Atif Bashir Fazari9Amar Hassan10Riad Bayoumi11Latifa Women and Children Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityRashid Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityRashid Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityLatifa Women and Children Hospital, Dubai Health AuthorityMohammed Bin Rashid University of Medicine and Health SciencesMohammed Bin Rashid University of Medicine and Health SciencesAbstract Background Whilst the impact of Covid-19 infection in pregnant women has been examined, there is a scarcity of data on pregnant women in the Middle East. Thus, the aim of this study was to examine the impact of Covid-19 infection on pregnant women in the United Arab Emirates population. Methods A case-control study was carried out to compare the clinical course and outcome of pregnancy in 79 pregnant women with Covid-19 and 85 non-pregnant women with Covid-19 admitted to Latifa Hospital in Dubai between March and June 2020. Results Although Pregnant women presented with fewer symptoms such as fever, cough, sore throat, and shortness of breath compared to non-pregnant women; yet they ran a much more severe course of illness. On admission, 12/79 (15.2%) Vs 2/85 (2.4%) had a chest radiograph score [on a scale 1-6] of ≥3 (p-value = 0.0039). On discharge, 6/79 (7.6%) Vs 1/85 (1.2%) had a score ≥3 (p-value = 0.0438). They also had much higher levels of laboratory indicators of severity with values above reference ranges for C-Reactive Protein [(28 (38.3%) Vs 13 (17.6%)] with p < 0.004; and for D-dimer [32 (50.8%) Vs 3(6%)]; with p < 0.001. They required more ICU admissions: 10/79 (12.6%) Vs 1/85 (1.2%) with p=0.0036; and suffered more complications: 9/79 (11.4%) Vs 1/85 (1.2%) with p=0.0066; of Covid-19 infection, particularly in late pregnancy. Conclusions Pregnant women presented with fewer Covid-19 symptoms but ran a much more severe course of illness compared to non-pregnant women with the disease. They had worse chest radiograph scores and much higher levels of laboratory indicators of disease severity. They had more ICU admissions and suffered more complications of Covid-19 infection, such as risk for miscarriage and preterm deliveries. Pregnancy with Covid-19 infection, could, therefore, be categorised as high-risk pregnancy and requires management by an obstetric and medical multidisciplinary team.https://doi.org/10.1186/s12884-021-04130-8Covid-19High-risk pregnancyNeonatePneumoniaNeonatal morbidityMaternal morbidity |
| spellingShingle | Komal Sundeep Hazari Rasha Abdeldayem Litty Paulose Nimmi Kurien Zukaa Almahloul Hozaifah Mohammad Taghrid Faek A. Elgergawi Maryam Alkhanbouli Khalid Mahmoud Atif Bashir Fazari Amar Hassan Riad Bayoumi Covid-19 infection in pregnant women in Dubai: a case-control study BMC Pregnancy and Childbirth Covid-19 High-risk pregnancy Neonate Pneumonia Neonatal morbidity Maternal morbidity |
| title | Covid-19 infection in pregnant women in Dubai: a case-control study |
| title_full | Covid-19 infection in pregnant women in Dubai: a case-control study |
| title_fullStr | Covid-19 infection in pregnant women in Dubai: a case-control study |
| title_full_unstemmed | Covid-19 infection in pregnant women in Dubai: a case-control study |
| title_short | Covid-19 infection in pregnant women in Dubai: a case-control study |
| title_sort | covid 19 infection in pregnant women in dubai a case control study |
| topic | Covid-19 High-risk pregnancy Neonate Pneumonia Neonatal morbidity Maternal morbidity |
| url | https://doi.org/10.1186/s12884-021-04130-8 |
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