Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study
Statement of the Problem: Every effort for increasing the calcium concentration in the saliva would be beneficial for prevention of dental caries. Regarding this issue, the natural products could be considered safer and more cost effective. Sesame is rich in calcium but the data about the effect of...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2022-06-01
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| Series: | Journal of Dentistry |
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| Online Access: | https://dentjods.sums.ac.ir/article_48357_2e783cea91f28028b02d2dbd9afc1eac.pdf |
| _version_ | 1797995746267496448 |
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| author | Faeze Hamze Leila Ghasemi Mohammad Kamalinejad |
| author_facet | Faeze Hamze Leila Ghasemi Mohammad Kamalinejad |
| author_sort | Faeze Hamze |
| collection | DOAJ |
| description | Statement of the Problem: Every effort for increasing the calcium concentration in the saliva would be beneficial for prevention of dental caries. Regarding this issue, the natural products could be considered safer and more cost effective. Sesame is rich in calcium but the data about the effect of sesame on enamel roughness is inadequate.
Purpose: This study aimed to assess the effect of an experimental sesame gel on the surface roughness of human enamel by using atomic force microscopy (AFM).
Materials and Method: In the current experimental study, fifteen enamel slices with 1mm thickness were prepared. They were polished and acid etched to produce a substantial rough surface prior to the first AFM analysis. The enamel blocks were randomly divided into three groups treated with distilled water, fluoride gel, and an experimental prepared sesame gel correspondingly. The treating agent was applied for 3minutes at 0, 8, 24, and 48h intervals and washed by distilled water after each cycles. Ultimately, the final AFM micrographs were prepared. The statistical analysis was performed using paired t-test, one-way ANOVA, and Tukey Post Hoc tests (=0.05).
Results: Statistical analysis revealed that the surface roughness was significantly reduced in both sesame and fluoride groups (p= 0.017 and 0.018, respectively) while the control group (distilled water) were not noticeably changed (p= 0.12). The control group had statistically significant difference with both the sesame and the fluoride groups (p= 0.007 and 0.007, respectively) while the there was no significance difference between sesame and fluoride groups (p= 0.997).
Conclusion: Following demineralization by acid etched process, the sesame gel significantly reduced surface roughness of enamel and its effect was similar to fluoride gel.
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| first_indexed | 2024-04-11T10:06:33Z |
| format | Article |
| id | doaj.art-b57287c99526432ca734211520d8003a |
| institution | Directory Open Access Journal |
| issn | 2345-6485 2345-6418 |
| language | English |
| last_indexed | 2024-04-11T10:06:33Z |
| publishDate | 2022-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dentistry |
| spelling | doaj.art-b57287c99526432ca734211520d8003a2022-12-22T04:30:14ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182022-06-01Supplement-June-2022Supplement-June-202216917410.30476/DENTJODS.2021.87878.1293Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy StudyFaeze Hamze 0Leila Ghasemi 1Mohammad Kamalinejad 2Dept. of Operative, Shahed University of Tehran, Tehran, Iran. Dept. of Operative, Dental School, Ilam University of Medical Sciences, Ilam, Iran.School of Pharmacy, Shahid Beheshti University of Medical Sciences (SBMU) Tehran, Iran.Statement of the Problem: Every effort for increasing the calcium concentration in the saliva would be beneficial for prevention of dental caries. Regarding this issue, the natural products could be considered safer and more cost effective. Sesame is rich in calcium but the data about the effect of sesame on enamel roughness is inadequate. Purpose: This study aimed to assess the effect of an experimental sesame gel on the surface roughness of human enamel by using atomic force microscopy (AFM). Materials and Method: In the current experimental study, fifteen enamel slices with 1mm thickness were prepared. They were polished and acid etched to produce a substantial rough surface prior to the first AFM analysis. The enamel blocks were randomly divided into three groups treated with distilled water, fluoride gel, and an experimental prepared sesame gel correspondingly. The treating agent was applied for 3minutes at 0, 8, 24, and 48h intervals and washed by distilled water after each cycles. Ultimately, the final AFM micrographs were prepared. The statistical analysis was performed using paired t-test, one-way ANOVA, and Tukey Post Hoc tests (=0.05). Results: Statistical analysis revealed that the surface roughness was significantly reduced in both sesame and fluoride groups (p= 0.017 and 0.018, respectively) while the control group (distilled water) were not noticeably changed (p= 0.12). The control group had statistically significant difference with both the sesame and the fluoride groups (p= 0.007 and 0.007, respectively) while the there was no significance difference between sesame and fluoride groups (p= 0.997). Conclusion: Following demineralization by acid etched process, the sesame gel significantly reduced surface roughness of enamel and its effect was similar to fluoride gel. https://dentjods.sums.ac.ir/article_48357_2e783cea91f28028b02d2dbd9afc1eac.pdfherbal; sesame; fluoride; remineralization; enamel; surface roughness |
| spellingShingle | Faeze Hamze Leila Ghasemi Mohammad Kamalinejad Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study Journal of Dentistry herbal; sesame; fluoride; remineralization; enamel; surface roughness |
| title | Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study |
| title_full | Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study |
| title_fullStr | Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study |
| title_full_unstemmed | Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study |
| title_short | Evaluating the Effect of an Experimental Sesame Gel on Human Enamel: Atomic Force Microscopy Study |
| title_sort | evaluating the effect of an experimental sesame gel on human enamel atomic force microscopy study |
| topic | herbal; sesame; fluoride; remineralization; enamel; surface roughness |
| url | https://dentjods.sums.ac.ir/article_48357_2e783cea91f28028b02d2dbd9afc1eac.pdf |
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