Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in <it>Escherichia coli</it>

Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in <it>Escherichia coli</it>

<p>Abstract</p> <p>Background</p> <p>Microbial engineering strategies that elicit global metabolic perturbations have the capacity to increase organism robustness for targeted metabolite production. In particular, perturbations to regulators of cellular systems that imp...

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Main Authors: McKee Adrienne E, Rutherford Becky J, Chivian Dylan C, Baidoo Edward K, Juminaga Darmawi, Kuo Dwight, Benke Peter I, Dietrich Jeffrey A, Ma Suzanne M, Arkin Adam P, Petzold Christopher J, Adams Paul D, Keasling Jay D, Chhabra Swapnil R
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Microbial Cell Factories
Subjects:
Metabolic engineering
Global regulators
Heterologous pathway
Carbon storage
Biofuels
Metabolomics
Proteomics
Online Access:http://www.microbialcellfactories.com/content/11/1/79

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