Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
Acremonium chrysogenum is an important filamentous fungus which produces cephalosporin C in industry. This review summarized the study on genetic engineering of Acremonium chrysogenum, including biosynthesis and regulation for fermentation of cephalosporin C, molecular techniques, molecular breeding...
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2016-09-01
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| Series: | Synthetic and Systems Biotechnology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405805X16300060 |
| _version_ | 1827279281542135808 |
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| author | Youjia Hu Baoquan Zhu |
| author_facet | Youjia Hu Baoquan Zhu |
| author_sort | Youjia Hu |
| collection | DOAJ |
| description | Acremonium chrysogenum is an important filamentous fungus which produces cephalosporin C in industry. This review summarized the study on genetic engineering of Acremonium chrysogenum, including biosynthesis and regulation for fermentation of cephalosporin C, molecular techniques, molecular breeding and transcriptomics of Acremonium chrysogenum. We believe with all the techniques available and full genomic sequence, the industrial strain of Acremonium chrysogenum can be genetically modified to better serve the pharmaceutical industry. |
| first_indexed | 2024-04-24T08:16:23Z |
| format | Article |
| id | doaj.art-b5784f8d61a44c308a6fab0c01980e0f |
| institution | Directory Open Access Journal |
| issn | 2405-805X |
| language | English |
| last_indexed | 2024-04-24T08:16:23Z |
| publishDate | 2016-09-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Synthetic and Systems Biotechnology |
| spelling | doaj.art-b5784f8d61a44c308a6fab0c01980e0f2024-04-17T03:42:03ZengKeAi Communications Co., Ltd.Synthetic and Systems Biotechnology2405-805X2016-09-011314314910.1016/j.synbio.2016.09.002Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producerYoujia HuBaoquan ZhuAcremonium chrysogenum is an important filamentous fungus which produces cephalosporin C in industry. This review summarized the study on genetic engineering of Acremonium chrysogenum, including biosynthesis and regulation for fermentation of cephalosporin C, molecular techniques, molecular breeding and transcriptomics of Acremonium chrysogenum. We believe with all the techniques available and full genomic sequence, the industrial strain of Acremonium chrysogenum can be genetically modified to better serve the pharmaceutical industry.http://www.sciencedirect.com/science/article/pii/S2405805X16300060Acremonium chrysogenumCephalosporin CGenetic engineeringMolecular breeding |
| spellingShingle | Youjia Hu Baoquan Zhu Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer Synthetic and Systems Biotechnology Acremonium chrysogenum Cephalosporin C Genetic engineering Molecular breeding |
| title | Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer |
| title_full | Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer |
| title_fullStr | Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer |
| title_full_unstemmed | Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer |
| title_short | Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer |
| title_sort | study on genetic engineering of acremonium chrysogenum the cephalosporin c producer |
| topic | Acremonium chrysogenum Cephalosporin C Genetic engineering Molecular breeding |
| url | http://www.sciencedirect.com/science/article/pii/S2405805X16300060 |
| work_keys_str_mv | AT youjiahu studyongeneticengineeringofacremoniumchrysogenumthecephalosporincproducer AT baoquanzhu studyongeneticengineeringofacremoniumchrysogenumthecephalosporincproducer |