Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study
AbstractThe development of regenerative endodontic therapy offers new opportunities for faster tooth recovery in chronic apical periodontitis. This study aimed to use three different surgical protocols to compare the results (filling the apical lesion with bone tissue over 6 months) of treatment in...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Biotechnology & Biotechnological Equipment |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/13102818.2022.2108338 |
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| author | Janet Kirilova Dimitar Kirov Dimitar Yovchev Snezhanka Topalova-Pirinska Elitsa Deliverska |
| author_facet | Janet Kirilova Dimitar Kirov Dimitar Yovchev Snezhanka Topalova-Pirinska Elitsa Deliverska |
| author_sort | Janet Kirilova |
| collection | DOAJ |
| description | AbstractThe development of regenerative endodontic therapy offers new opportunities for faster tooth recovery in chronic apical periodontitis. This study aimed to use three different surgical protocols to compare the results (filling the apical lesion with bone tissue over 6 months) of treatment in patients with chronic apical periodontitis. This study included 23 patients and 30 teeth with chronic apical periodontitis. The patients were divided into three groups: (1) Endodontic treatment and apical osteotomy without filling; (2) Endodontic treatment and apical osteotomy with the placement of blood concentrate according to the advanced platelet-rich fibrin A-PRF + protocol; (3) Endodontic treatment and apical osteotomy with the placement of blood concentrate according to the ‘sticky bone’ and A-PRF + protocols with allograft. The results were reported after 6 months using cone-beam computed tomography. The results showed a statistically significant difference (Mann–Whitney U test) in the filling of the bone defect in the healing process between the first group (average rank 31.490) and the second group (average rank 96.015), as well as between the first group (average rank 31.490) and the third group (average rank 91.765). No significant difference was found in the filling of the bone defects between the second and third groups. We show that placement of A-PRF + blood concentrate alone or combined with alloplastic graft after classical apical osteotomy of teeth with chronic apical periodontitis leads to a size reduction of the bone defect with 95.25% for group 2 and 90.80% for group 3 after 6 months. |
| first_indexed | 2024-04-11T04:15:30Z |
| format | Article |
| id | doaj.art-b57f4d297213446ab454f51ece5952cd |
| institution | Directory Open Access Journal |
| issn | 1310-2818 1314-3530 |
| language | English |
| last_indexed | 2024-04-11T04:15:30Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Biotechnology & Biotechnological Equipment |
| spelling | doaj.art-b57f4d297213446ab454f51ece5952cd2022-12-31T18:03:16ZengTaylor & Francis GroupBiotechnology & Biotechnological Equipment1310-28181314-35302022-12-0136173774410.1080/13102818.2022.2108338Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical studyJanet Kirilova0Dimitar Kirov1Dimitar Yovchev2Snezhanka Topalova-Pirinska3Elitsa Deliverska4Department of Conservative Dentistry, Faculty of Dental Medicine, Medical University of Sofia, Sofia, BulgariaDepartment of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University of Sofia, Sofia, BulgariaDepartment of Imaging and Oral Diagnostic, Faculty of Dental Medicine, Medical University of Sofia, Sofia, BulgariaDepartment of Conservative Dentistry, Faculty of Dental Medicine, Medical University of Sofia, Sofia, BulgariaDepartment of Maxillofacial Surgery, Faculty of Dental Medicine, Medical University of Sofia, Sofia, BulgariaAbstractThe development of regenerative endodontic therapy offers new opportunities for faster tooth recovery in chronic apical periodontitis. This study aimed to use three different surgical protocols to compare the results (filling the apical lesion with bone tissue over 6 months) of treatment in patients with chronic apical periodontitis. This study included 23 patients and 30 teeth with chronic apical periodontitis. The patients were divided into three groups: (1) Endodontic treatment and apical osteotomy without filling; (2) Endodontic treatment and apical osteotomy with the placement of blood concentrate according to the advanced platelet-rich fibrin A-PRF + protocol; (3) Endodontic treatment and apical osteotomy with the placement of blood concentrate according to the ‘sticky bone’ and A-PRF + protocols with allograft. The results were reported after 6 months using cone-beam computed tomography. The results showed a statistically significant difference (Mann–Whitney U test) in the filling of the bone defect in the healing process between the first group (average rank 31.490) and the second group (average rank 96.015), as well as between the first group (average rank 31.490) and the third group (average rank 91.765). No significant difference was found in the filling of the bone defects between the second and third groups. We show that placement of A-PRF + blood concentrate alone or combined with alloplastic graft after classical apical osteotomy of teeth with chronic apical periodontitis leads to a size reduction of the bone defect with 95.25% for group 2 and 90.80% for group 3 after 6 months.https://www.tandfonline.com/doi/10.1080/13102818.2022.2108338Chronic apical periodontitisregenerative endodontic therapyplatelet-rich fibrincone-beam computed tomographyapical surgerytreatment outcomes |
| spellingShingle | Janet Kirilova Dimitar Kirov Dimitar Yovchev Snezhanka Topalova-Pirinska Elitsa Deliverska Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study Biotechnology & Biotechnological Equipment Chronic apical periodontitis regenerative endodontic therapy platelet-rich fibrin cone-beam computed tomography apical surgery treatment outcomes |
| title | Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study |
| title_full | Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study |
| title_fullStr | Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study |
| title_full_unstemmed | Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study |
| title_short | Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study |
| title_sort | endodontic and surgical treatment of chronic apical periodontitis a randomized clinical study |
| topic | Chronic apical periodontitis regenerative endodontic therapy platelet-rich fibrin cone-beam computed tomography apical surgery treatment outcomes |
| url | https://www.tandfonline.com/doi/10.1080/13102818.2022.2108338 |
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