Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells
Diabetes mellitus currently affects ∼10% of the population worldwide, with Type 2 predominating, and this incidence is increasing steadily. Both Type 1 and 2 are complex diseases, involving β-cell death and chronic inflammation, but the pathways involved are unresolved. Chronic inflammation is chara...
Main Authors: | Ramona Clemen, Eduardo Fuentes-Lemus, Sander Bekeschus, Michael J. Davies |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
|
Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231723002367 |
Similar Items
-
Role and Cytotoxicity of Amylin and Protection of Pancreatic Islet β-Cells from Amylin Cytotoxicity
by: Yoshimitsu Kiriyama, et al.
Published: (2018-08-01) -
Boronate-Based Probes for Biological Oxidants: A Novel Class of Molecular Tools for Redox Biology
by: Adam Sikora, et al.
Published: (2020-09-01) -
Argon Plasma Exposure Augments Costimulatory Ligands and Cytokine Release in Human Monocyte-Derived Dendritic Cells
by: Sander Bekeschus, et al.
Published: (2021-04-01) -
The Effect of Cholesterol on Membrane-Bound Islet Amyloid Polypeptide
by: Mikkel Christensen, et al.
Published: (2021-04-01) -
Serum amylin level in Behçet’s disease and relation to parameters of metabolic syndrome and disease activity
by: Shimaa M Abdelwhab, et al.
Published: (2018-01-01)