Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering
Muconic acid is a platform chemical with wide industrial applicability. Here, the authors report efficient muconate production from glucose and xylose by engineered Pseudomonas putida strain using adaptive laboratory evolution, metabolic modeling, and rational strain engineering strategies.
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32296-y |
| _version_ | 1811183296935100416 |
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| author | Chen Ling George L. Peabody Davinia Salvachúa Young-Mo Kim Colin M. Kneucker Christopher H. Calvey Michela A. Monninger Nathalie Munoz Munoz Brenton C. Poirier Kelsey J. Ramirez Peter C. St. John Sean P. Woodworth Jon K. Magnuson Kristin E. Burnum-Johnson Adam M. Guss Christopher W. Johnson Gregg T. Beckham |
| author_facet | Chen Ling George L. Peabody Davinia Salvachúa Young-Mo Kim Colin M. Kneucker Christopher H. Calvey Michela A. Monninger Nathalie Munoz Munoz Brenton C. Poirier Kelsey J. Ramirez Peter C. St. John Sean P. Woodworth Jon K. Magnuson Kristin E. Burnum-Johnson Adam M. Guss Christopher W. Johnson Gregg T. Beckham |
| author_sort | Chen Ling |
| collection | DOAJ |
| description | Muconic acid is a platform chemical with wide industrial applicability. Here, the authors report efficient muconate production from glucose and xylose by engineered Pseudomonas putida strain using adaptive laboratory evolution, metabolic modeling, and rational strain engineering strategies. |
| first_indexed | 2024-04-11T09:45:40Z |
| format | Article |
| id | doaj.art-b5842f1b194c4c5081ddd1bbb47e1529 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T09:45:40Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b5842f1b194c4c5081ddd1bbb47e15292022-12-22T04:31:05ZengNature PortfolioNature Communications2041-17232022-08-0113111410.1038/s41467-022-32296-yMuconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineeringChen Ling0George L. Peabody1Davinia Salvachúa2Young-Mo Kim3Colin M. Kneucker4Christopher H. Calvey5Michela A. Monninger6Nathalie Munoz Munoz7Brenton C. Poirier8Kelsey J. Ramirez9Peter C. St. John10Sean P. Woodworth11Jon K. Magnuson12Kristin E. Burnum-Johnson13Adam M. Guss14Christopher W. Johnson15Gregg T. Beckham16Renewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryAgile BioFoundryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryAgile BioFoundryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryAgile BioFoundryAgile BioFoundryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryAgile BioFoundryAgile BioFoundryAgile BioFoundryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryRenewable Resources and Enabling Sciences Center, National Renewable Energy LaboratoryMuconic acid is a platform chemical with wide industrial applicability. Here, the authors report efficient muconate production from glucose and xylose by engineered Pseudomonas putida strain using adaptive laboratory evolution, metabolic modeling, and rational strain engineering strategies.https://doi.org/10.1038/s41467-022-32296-y |
| spellingShingle | Chen Ling George L. Peabody Davinia Salvachúa Young-Mo Kim Colin M. Kneucker Christopher H. Calvey Michela A. Monninger Nathalie Munoz Munoz Brenton C. Poirier Kelsey J. Ramirez Peter C. St. John Sean P. Woodworth Jon K. Magnuson Kristin E. Burnum-Johnson Adam M. Guss Christopher W. Johnson Gregg T. Beckham Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering Nature Communications |
| title | Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering |
| title_full | Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering |
| title_fullStr | Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering |
| title_full_unstemmed | Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering |
| title_short | Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering |
| title_sort | muconic acid production from glucose and xylose in pseudomonas putida via evolution and metabolic engineering |
| url | https://doi.org/10.1038/s41467-022-32296-y |
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