Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma
Objectives: The aim of the present study was to describe the computed tomography (CT) characteristics of primary liver carcinosarcoma (PLCS) and to explore the pathological basis for the diagnosis of primary hepatocellular carcinoma sarcoma.Methods: Three male patients with PLCS were included in the...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-06-01
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| Series: | Frontiers in Genetics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2021.638636/full |
| _version_ | 1818873531028471808 |
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| author | Lu Huang Lijian Lu |
| author_facet | Lu Huang Lijian Lu |
| author_sort | Lu Huang |
| collection | DOAJ |
| description | Objectives: The aim of the present study was to describe the computed tomography (CT) characteristics of primary liver carcinosarcoma (PLCS) and to explore the pathological basis for the diagnosis of primary hepatocellular carcinoma sarcoma.Methods: Three male patients with PLCS were included in the present retrospective research, and the age was ranged from 52 to 63 years. The plain CT scan and third-stage enhancement scan were performed on patients. The pathological characteristics were analyzed. Stomachache was the main clinical symptoms of the three patients. Cirrhosis background was confirmed in one patients, and chronic Hepatitis B background was confirmed in other two patients.Results: According to the results of CT, the inner diameter of the tumors ranged from 8.6 to 27.0 cm. The fibrous pseudocapsule around the tumor tissues was observed in two patients. Tumor tissues from all three patients were composed of sarcomatous and carcinomatous components. For carcinomatous components, hepatocellular carcinoma was observed in one patient and cholangiocarcinoma was observed in the other two patients. For sarcomatous components, angiosarcoma was observed in two patients and malignant fibrous histiocytoma was observed in another one patient. The tumor tissues were visualized as heterogeneous low density with large sheets of necrotic cystic lesions or thick-walled areas of multilocular cystic lesions using the plain CT scan. Edge-to-center filling and strengthening lesions, mild to moderate enhanced parenchyma at the arterial phase, and isodensity between the tumor parenchyma and the surrounding liver parenchyma at the portal vein phase or delayed phase were observed using the third-stage enhancement scan.Conclusions: CT characteristics observed in the present study were of great benefit for the diagnosis of PLCS. |
| first_indexed | 2024-12-19T12:56:11Z |
| format | Article |
| id | doaj.art-b5866cd5ee044d9abc74f970a978c856 |
| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-12-19T12:56:11Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj.art-b5866cd5ee044d9abc74f970a978c8562022-12-21T20:20:23ZengFrontiers Media S.A.Frontiers in Genetics1664-80212021-06-011210.3389/fgene.2021.638636638636Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver CarcinosarcomaLu Huang0Lijian Lu1Department of Infectious Diseases, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Radiology, The Wuming Affiliated Hospital of Guangxi Medical University, Nanning, ChinaObjectives: The aim of the present study was to describe the computed tomography (CT) characteristics of primary liver carcinosarcoma (PLCS) and to explore the pathological basis for the diagnosis of primary hepatocellular carcinoma sarcoma.Methods: Three male patients with PLCS were included in the present retrospective research, and the age was ranged from 52 to 63 years. The plain CT scan and third-stage enhancement scan were performed on patients. The pathological characteristics were analyzed. Stomachache was the main clinical symptoms of the three patients. Cirrhosis background was confirmed in one patients, and chronic Hepatitis B background was confirmed in other two patients.Results: According to the results of CT, the inner diameter of the tumors ranged from 8.6 to 27.0 cm. The fibrous pseudocapsule around the tumor tissues was observed in two patients. Tumor tissues from all three patients were composed of sarcomatous and carcinomatous components. For carcinomatous components, hepatocellular carcinoma was observed in one patient and cholangiocarcinoma was observed in the other two patients. For sarcomatous components, angiosarcoma was observed in two patients and malignant fibrous histiocytoma was observed in another one patient. The tumor tissues were visualized as heterogeneous low density with large sheets of necrotic cystic lesions or thick-walled areas of multilocular cystic lesions using the plain CT scan. Edge-to-center filling and strengthening lesions, mild to moderate enhanced parenchyma at the arterial phase, and isodensity between the tumor parenchyma and the surrounding liver parenchyma at the portal vein phase or delayed phase were observed using the third-stage enhancement scan.Conclusions: CT characteristics observed in the present study were of great benefit for the diagnosis of PLCS.https://www.frontiersin.org/articles/10.3389/fgene.2021.638636/fulllivertumoratomographyx-ray computeddiagnosis |
| spellingShingle | Lu Huang Lijian Lu Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma Frontiers in Genetics liver tumora tomography x-ray computed diagnosis |
| title | Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma |
| title_full | Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma |
| title_fullStr | Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma |
| title_full_unstemmed | Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma |
| title_short | Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma |
| title_sort | case report review of ct findings and histopathological characteristics of primary liver carcinosarcoma |
| topic | liver tumora tomography x-ray computed diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fgene.2021.638636/full |
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