Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?

On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (or Aβ) plaques from the brain.

Bibliographic Details
Main Authors: Giovanna Lalli, Jonathan M Schott, John Hardy, Bart De Strooper
Format: Article
Language:English
Published: Springer Nature 2021-08-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202114781
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author Giovanna Lalli
Jonathan M Schott
John Hardy
Bart De Strooper
author_facet Giovanna Lalli
Jonathan M Schott
John Hardy
Bart De Strooper
author_sort Giovanna Lalli
collection DOAJ
description On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (or Aβ) plaques from the brain.
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spelling doaj.art-b58865ed2caa4598874cf2c4fbbe5fbf2024-03-02T11:20:35ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842021-08-01138n/an/a10.15252/emmm.202114781Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?Giovanna Lalli0Jonathan M Schott1John Hardy2Bart De Strooper3UK Dementia Research Institute at UCL London UKDementia Research Centre UCL Queen Square Institute of Neurology London UKUK Dementia Research Institute at UCL London UKUK Dementia Research Institute at UCL London UKOn 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (or Aβ) plaques from the brain.https://doi.org/10.15252/emmm.202114781
spellingShingle Giovanna Lalli
Jonathan M Schott
John Hardy
Bart De Strooper
Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
EMBO Molecular Medicine
title Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_full Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_fullStr Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_full_unstemmed Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_short Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_sort aducanumab a new phase in therapeutic development for alzheimer s disease
url https://doi.org/10.15252/emmm.202114781
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AT bartdestrooper aducanumabanewphaseintherapeuticdevelopmentforalzheimersdisease