Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers
In East Africa, <i>Dodonaea angustifolia</i> (L.f.) is a well-known medicinal herb. Its leaf is primarily studied in light of its ethnobotanical use. In terms of phytochemistry and biological activity, its flower is not studied. In a prior study, our team looked into phytochemical screen...
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MDPI AG
2023-03-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/6/2870 |
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| author | Fekade Beshah Tessema Yilma Hunde Gonfa Tilahun Belayneh Asfaw Mesfin Getachew Tadesse Tigist Getachew Tadesse Archana Bachheti Mohammed O. Alshaharni Pankaj Kumar Vinod Kumar Ivan Širić Sami Abou Fayssal Kundan Kumar Chaubey Rakesh Kumar Bachheti |
| author_facet | Fekade Beshah Tessema Yilma Hunde Gonfa Tilahun Belayneh Asfaw Mesfin Getachew Tadesse Tigist Getachew Tadesse Archana Bachheti Mohammed O. Alshaharni Pankaj Kumar Vinod Kumar Ivan Širić Sami Abou Fayssal Kundan Kumar Chaubey Rakesh Kumar Bachheti |
| author_sort | Fekade Beshah Tessema |
| collection | DOAJ |
| description | In East Africa, <i>Dodonaea angustifolia</i> (L.f.) is a well-known medicinal herb. Its leaf is primarily studied in light of its ethnobotanical use. In terms of phytochemistry and biological activity, its flower is not studied. In a prior study, our team looked into phytochemical screening, antioxidant activity, and total phenolic levels. This study aims to compare the profiles and biological activities of the leaf and flower samples of <i>D. angustifolia</i> and to present therapeutic alternatives. The leaf and flower sample powders were extracted with methanol using ultrasound-assisted extraction (UAE). HPTLC profile was obtained using CAMAG—HPTLC equipped with VisionCATS software. Antimicrobial agar well diffusion assay and minimum inhibition concentration (MIC) were determined. The leaf and flower extracts of <i>D. angustifolia</i> showed antibacterial activity with a MIC value of 20 µg/mL against <i>Enterococcus faecalis</i> and <i>Listeria monocytogenes</i>. Similarly, 40 µg/mL was found to be effective against <i>Aspergillus flavus</i>. <i>D. angustifolia</i> flower is a rich source of flavonoids and phenolic acids. Because of its antibacterial properties and profile, which are almost the same, the flower is emerging as a viable option for medicinal alternatives. |
| first_indexed | 2024-03-11T06:06:26Z |
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| id | doaj.art-b5892286674845969f40b2d439c9af4e |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T06:06:26Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-b5892286674845969f40b2d439c9af4e2023-11-17T12:56:20ZengMDPI AGMolecules1420-30492023-03-01286287010.3390/molecules28062870Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and FlowersFekade Beshah Tessema0Yilma Hunde Gonfa1Tilahun Belayneh Asfaw2Mesfin Getachew Tadesse3Tigist Getachew Tadesse4Archana Bachheti5Mohammed O. Alshaharni6Pankaj Kumar7Vinod Kumar8Ivan Širić9Sami Abou Fayssal10Kundan Kumar Chaubey11Rakesh Kumar Bachheti12Department of Industrial Chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 16417, EthiopiaDepartment of Industrial Chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 16417, EthiopiaDepartment of Industrial Chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 16417, EthiopiaDepartment of Industrial Chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 16417, EthiopiaBio and Emerging Technology Institute, Health Biotechnology Directorate, Addis Ababa P.O. Box 5954, EthiopiaDepartment of Environment Science, Graphic Era (Deemed to be University), Dehradun 248002, IndiaDepartment of Biology, College of Science, King Khalid University, Abha 61321, Saudi ArabiaAgro-Ecology and Pollution Research Laboratory, Department of Zoology and Environmental Science, Gurukula Kangri (Deemed to Be University), Haridwar 249404, IndiaAgro-Ecology and Pollution Research Laboratory, Department of Zoology and Environmental Science, Gurukula Kangri (Deemed to Be University), Haridwar 249404, IndiaUniversity of Zagreb, Faculty of Agriculture, Svetosimunska 25, 10000 Zagreb, CroatiaDepartment of Agronomy, Faculty of Agronomy, University of Forestry, 10 Kliment Ohridski Blvd, 1797 Sofia, BulgariaDivision of Research and Innovation, School of Applied and Life Sciences, Uttaranchal University, Arcadia Grant, P.O. Chandanwari, Prem Nagar, Dehradun 248007, IndiaDepartment of Industrial Chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O. Box 16417, EthiopiaIn East Africa, <i>Dodonaea angustifolia</i> (L.f.) is a well-known medicinal herb. Its leaf is primarily studied in light of its ethnobotanical use. In terms of phytochemistry and biological activity, its flower is not studied. In a prior study, our team looked into phytochemical screening, antioxidant activity, and total phenolic levels. This study aims to compare the profiles and biological activities of the leaf and flower samples of <i>D. angustifolia</i> and to present therapeutic alternatives. The leaf and flower sample powders were extracted with methanol using ultrasound-assisted extraction (UAE). HPTLC profile was obtained using CAMAG—HPTLC equipped with VisionCATS software. Antimicrobial agar well diffusion assay and minimum inhibition concentration (MIC) were determined. The leaf and flower extracts of <i>D. angustifolia</i> showed antibacterial activity with a MIC value of 20 µg/mL against <i>Enterococcus faecalis</i> and <i>Listeria monocytogenes</i>. Similarly, 40 µg/mL was found to be effective against <i>Aspergillus flavus</i>. <i>D. angustifolia</i> flower is a rich source of flavonoids and phenolic acids. Because of its antibacterial properties and profile, which are almost the same, the flower is emerging as a viable option for medicinal alternatives.https://www.mdpi.com/1420-3049/28/6/2870antimicrobial activities<i>Dodonaea angustifolia</i>flavonoidsmedicinal plantsphenolic contents |
| spellingShingle | Fekade Beshah Tessema Yilma Hunde Gonfa Tilahun Belayneh Asfaw Mesfin Getachew Tadesse Tigist Getachew Tadesse Archana Bachheti Mohammed O. Alshaharni Pankaj Kumar Vinod Kumar Ivan Širić Sami Abou Fayssal Kundan Kumar Chaubey Rakesh Kumar Bachheti Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers Molecules antimicrobial activities <i>Dodonaea angustifolia</i> flavonoids medicinal plants phenolic contents |
| title | Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers |
| title_full | Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers |
| title_fullStr | Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers |
| title_full_unstemmed | Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers |
| title_short | Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of <i>Dodonaea angustifolia</i> (L.f.) Leaves and Flowers |
| title_sort | targeted hptlc profile quantification of flavonoids and phenolic acids and antimicrobial activity of i dodonaea angustifolia i l f leaves and flowers |
| topic | antimicrobial activities <i>Dodonaea angustifolia</i> flavonoids medicinal plants phenolic contents |
| url | https://www.mdpi.com/1420-3049/28/6/2870 |
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